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Biotransformations of α-terpineol in the rat: Its effects on the liver microsomal cytochrome P-450 system

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References

  • Chadha A, Madyastha KM (1982) w-Hydroxylation of acyclic monoterpene alcohols by rat lung microsomes. Biochem Biophys Res Commun 108:1271–1277

    PubMed  Google Scholar 

  • Chadha A, Madyastha KM (1984) Metabolism of geraniol and linalool in the rat and effects on liver and lung microsomal enzymes. Xenobiotica 14:365–374

    PubMed  Google Scholar 

  • Cinti DL, Lemelin MA, Christian J (1976) Induction of liver microsomal mixed-function oxidases by volatile hydrocarbons. Biochem Pharm 25:100–103

    PubMed  Google Scholar 

  • Horning MG, Butler CM, Stafford M, Stillwell RN, Hill RM, Zion TE, Harvey DJ, Stillwell WG (1976) In: Advances in mass spectrometry in biochemistry and medicine (Eds Frigerio A, Catagnoli N). Spectrum Publications New York Vol 1, p 91

    Google Scholar 

  • Ishida T, Asakawa Y, Takemoto T, Aratani T (1981) Terpenoids biotransformation in mammals III: Biotransformation of α-pinene, β-pinene, pinane, 3-carene, carane, myrcene and p-cymene in rabbits. J Pharm Sci 70: 406–415

    PubMed  Google Scholar 

  • Jarvisalo J, Vainio N (1980) Enhancement of hepatic drug biotransformation by a short-term intermittent turpentine exposure in rat. Acta Pharmacol Toxicol 46: 32–36.

    Google Scholar 

  • Jori A, Bianchetti A, Prestini PE (1969) Effect of essential oils on drug-metabolism. Biochem Pharmac 18:2081–2085

    Google Scholar 

  • Kodama R, Noda K. Ide H (1974) Studies on the metabolism of d-limonene. II The metabolic fate of d-limonene in rabbits. Xenobiotica 4:85–95

    Google Scholar 

  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193:265–275

    PubMed  Google Scholar 

  • Lu AYH, Levin W (1972) Partial purification of cytochrome P-450 and P-448 from rat liver microsomes. Biochem Biophys Res Commun 46:1334–1339

    PubMed  Google Scholar 

  • Madyastha KM, Renganathan V (1983) Biodegradation of acetates of geraniol, nerol and citronellol byP.incognita: Isolation and identification of metabolites. Indian J Biochem Biophys 20:136–140

    PubMed  Google Scholar 

  • Madyastha KM, Renganathan V (1984) Metabolism of (α-terpineol byP.incognita. Can J Microbiol 30:1429–1436

    PubMed  Google Scholar 

  • Madyastha KM, Chadha A (1986) Metabolism of 1,8-cineole in rat. Its effects on liver and lung microsomal cytochrome P-450 systems. Bull Environ Contam Toxicol 37:759–766

    PubMed  Google Scholar 

  • Omura T, Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. J Biol Chem 239:2370–2378

    PubMed  Google Scholar 

  • Parke DV, Rahman H (1969) The effects of some terpenoids and other dietry anutrients on hepatic drug-metabolizing enzymes. Biochem J 113:12P

    Google Scholar 

  • Shukla OP, Moholay MN, Bhattacharyya PK (1968) Fermentation of α- and β-pinenes by a soil pseudomonad. Indian J Biochem 5:79–91

    Google Scholar 

  • Ventura P, Schiavi M, Serafini S, Selva A (1985) Further studies of trans-sobrerol metabolism: rat, dog and human urine. Xenobiotica 15:317–325

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Bio-Organic Section, Department of Organic Chemistry, Indian Institute of Science, 560 012, Bangalore, India

    K. Madhava Madyastha & V. Srivatsan

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  1. K. Madhava Madyastha
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  2. V. Srivatsan
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Madyastha, K.M., Srivatsan, V. Biotransformations of α-terpineol in the rat: Its effects on the liver microsomal cytochrome P-450 system. Bull. Environ. Contam. Toxicol. 41, 17–25 (1988). https://doi.org/10.1007/BF01689054

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  • DOI: https://doi.org/10.1007/BF01689054

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