Abstract
The human gene for the transformation-associated p53 phosphoprotein (P53)was assigned to the short arm of chromosome 17 using human-rodent somatic cell hybrids and Southern filter hybridization of cell hybrid DNA. The filters were hybridized to radiolabeled DNA from a genomic clone which contained P53nucleotide sequences. Hybridization of the probe to a 2.5-kb human DNA fragment in HindIII-digested DNA was used to identify the human P53gene.
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Benchimol, S., Lamb, P., Crawford, L.V. et al. Transformation associated p53 protein is encoded by a gene on human chromosome 17. Somat Cell Mol Genet 11, 505–510 (1985). https://doi.org/10.1007/BF01534845
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DOI: https://doi.org/10.1007/BF01534845