Skip to main content
Log in

Tissue ascorbic acid concentrations in rats experimentally infected withFasciola hepatica

  • Original Investigations
  • Published:
Zeitschrift für Parasitenkunde Aims and scope Submit manuscript

Abstract

Ascorbic acid concentrations were determined in livers, spleens and kidneys of 27 white rats infected withFasciola hepatica and 15 controls. Tissue ascorbic acid levels were consistently lower in infected animals and this was associated with decreased liver total proteins and glycogen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Barnes MJ (1975) Functions of ascorbic acid in collagen metabolism. Ann NY Acad Sci 258:264–277

    Google Scholar 

  • Charlton RW, Bothwell TH (1976) Iron, ascorbic acid and thalassemia. Birth Defects 12:63–79

    Google Scholar 

  • Combs GF Jr, Pesti GM (1976) Influence of ascorbic acid on selenium nutrition in the chick. J Nutr 106:958–966

    Google Scholar 

  • Denson KW, Bowers EF (1961) The determination of ascorbic acid in white blood cells. A comparison of WBC ascorbic acid and phenolic acid excretion of elderly patients. Clin Sci 21:157–162

    Google Scholar 

  • Gameel AA (1982) Plasma ascorbic acid levels in sheep experimentally infected withFasciola hepatica. Z Parasitenkd 66:321–326

    Google Scholar 

  • Gipp WF, Pond WG, Kallfelz FA, Tasker JB, Van Campen DR, Krook L, Visek WJ (1974) Effect of dietary copper, iron and ascorbic acid levels on haematology, blood and tissue copper, iron and zinc concentrations and64Cu and59Fe metabolism in young pigs. J Nutr 104:532–541

    Google Scholar 

  • Hawkins CD, Morris RS (1978) Depression of productivity in sheep infected withFasciola hepatica. Vet Parasit 4:341–351

    Google Scholar 

  • Kadziolka A (1962) Distribution of glycogen and vitamin C in the liver of cattle affected with parasitic cirrhosis (fascioliasis) (English summary). Med Wet (Warszawa) 18:93–99

    Google Scholar 

  • Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275

    Google Scholar 

  • Morris DL (1948) The quantitative determination of carbohydrates with Dreywood's anthrone reagent. Science 107:254–255

    Google Scholar 

  • Subramanian N, Nandi BK, Majumder AK, Chatterjee IB (1973) Role of ascorbic acid on detoxification of histamine. Biochem Pharmacol 22:1671–1673

    Google Scholar 

  • Turely SD, West CE, Horton BJ (1976) The role of ascorbic acid in the regulation of cholesterol metabolism and in the pathogenesis of atherosclerosis. Atherosclerosis 24:1–18

    Google Scholar 

  • Wilson CWM (1974) Vitamins and drug metabolism with particular reference to vitamin C. Proc Nutr Soc 33:231–238

    Google Scholar 

  • Ziolo T (1960) Distribution of cholesterol and vitamin C in the adrenal cortex of sheep with cirrhosis of the liver due to fascioliasis (English summary). Med Wet (Warszawa) 16:646–652

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gameel, A.A. Tissue ascorbic acid concentrations in rats experimentally infected withFasciola hepatica . Z. Parasitenkd. 68, 181–184 (1982). https://doi.org/10.1007/BF00935059

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00935059

Keywords

Navigation