Abstract
By the condensation of 3,4-diaminothiocoumarins containing primary or secondary amino groups in position 4, with formic and acetic acids (or acetic anhydrides), a number of 1H-[1]benzothiopyrano[3,4-d]imidazol-4-ones and their 2-methyl derivatives have been synthesized; the latter have also been obtained from the corresponding 3-monoacetylamino-4-aminothiocoumarins. By the acetylation of 3-4-diaminothiocoumarins with tertiary amino groups in positions 4 their 3-diacetyl derivative has been obtained, and these, under the action of bases, have been converted into 3-N-acetyl derivatives. The structures of the compounds synthesized have been confirmed by IR, PMR, and mass spectroscopy.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 479–483, April, 1980.
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Savel'ev, V.L., Afanas'eva, T.G., Klyuev, S.M. et al. Synthesis of 1H-[1]benzothiopyrano[3,4-d]imidazol-4-ones. Chem Heterocycl Compd 16, 363–367 (1980). https://doi.org/10.1007/BF00552775
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DOI: https://doi.org/10.1007/BF00552775