Summary
Evidence is presented that differentiating systems are closed off from their environment and self-sufficient; they must therefore operate on an endogenous metabolism. This fundamental characteristic of differentiation is exmained from the point of view of its evolution and with respect to the initiation, control and consumation of morphogenesis.
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Dedicated to Prof. C. B. van Niel for his 70th birthday. Kees introduced me to the slime molds, and they, in turn, introduced me to these speculations about their evolution.
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Wright, B.E. On the evolution of differentiation. Archiv. Mikrobiol. 59, 335–344 (1967). https://doi.org/10.1007/BF00406347
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DOI: https://doi.org/10.1007/BF00406347