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The human HLA specific monoclonal antibody W6/32 recognizes a discontinuous epitope within the α2 domain of murine H-2Db

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Abbreviations

mAb:

monoclonal antibody

MHC:

major histocompatibility complex

FITC:

fluorescein isothiocyanate

References

  • Allen, H., Wraith, D., Pala, P., Askonas, B., and Flavell, R.: Domain interactions of H-2 class I antigens after cytotoxic T -cell recognition sites. Nature 309: 279–281, 1984

    Google Scholar 

  • Brodsky, R. M., Parham, P., Barnstable, C., Crumpton, M., and Bodmer, W.: Monoclonal antibodies for analysis of the HLA system. Immunol. Rev. 47: 3–61, 1979

    Google Scholar 

  • Engelhard, V., Yannelli, J., Evans, G., Walk, S., and Holterman, M.: Construction of novel class I histocompatibility antigens by interspecies exon shuffling. J. Immunol. 134: 4218–4225, 1985

    Google Scholar 

  • Ivanyi, D. and Van de Meugheuvel, W.: A monomorphic HLA-specific monoclonal antibody, W6/32, reacts with the H-2Db molecule of normal mouse lymphocytes. Immunogenetics 20: 699–703, 1984

    Google Scholar 

  • Lopez de Castro, J., Barbosa, J., Krangel, M., Biro, P., and Strominger, J.: Structural analysis of the functional sites of class I HLA antigens. Immunol. Rev. 85: 149–168, 1985

    Google Scholar 

  • Maziarz, R., Allen, H., Strominger, J., Flavell, R., Biro, P., and Burakoff, S.: Recognition of interspecies hybrid class I histocompatibility antigens by antigen-specific cytolytic T lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 82: 6276–6280, 1985

    Google Scholar 

  • Ploegh, H., Cannon, L., and Strominger, J.: Cell free translation of the mRNA's for the heavy and light chains of HLA A and HLA-B antigens. Proc. Natl. Acad. Sci. U.S.A. 76: 2273–2277, 1979

    Google Scholar 

  • Tainer, J., Getzoff, E., Paterson, Y., Olson, A., and Lerner, R.: The atomic mobility component of protein antigenicity. Annu. Rev. Immunol. 3: 501–535, 1985

    Google Scholar 

  • Vega, M., Bragado, R., Ezguerra, A., and Lopez de Castro, J.: Variability and conformation of HLA class I antigens: A predictive approach to the spatial arrangement of the polymorphic regions. Biochemistry 23: 823–831, 1984

    Google Scholar 

  • Ways, J., Coppin, H., and Parham, P.: The complete primary structure of HLA BW 58. J. Biol. Chem. 260: 11924–11933, 1985

    Google Scholar 

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Maziarz, R.T., Fraser, J., Strominger, J.L. et al. The human HLA specific monoclonal antibody W6/32 recognizes a discontinuous epitope within the α2 domain of murine H-2Db . Immunogenetics 24, 206–208 (1986). https://doi.org/10.1007/BF00364750

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  • DOI: https://doi.org/10.1007/BF00364750

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