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Antibody removal and subsequent transplantation of a highly sensitised paediatric renal patient

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Transplant International

Abstract

We report a successful renal transplant in a highly sensitised paediatric recipient following removal of HLA-specific antibodies by extracorporeal immunoadsorption. The immediate pretransplant cytotoxic titre against the donor was greater than 1:512; this was reduced to negativity by two immunoadsorption sessions prior to transplant surgery. We also describe the presence of unexpected non-HLA-specific antibody activities in this immunoadsorbed patient.

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Beyan, D.J., Carey, B.S., Lea, C.K. et al. Antibody removal and subsequent transplantation of a highly sensitised paediatric renal patient. Transpl Int 9, 155–160 (1996). https://doi.org/10.1007/BF00336394

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  • DOI: https://doi.org/10.1007/BF00336394

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