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Retinal migraine, chorea, and retinal artery thrombosis in a patient with primary antiphospholipid antibody syndrome

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Summary

We report the case of a patient with the unusual combination of migraine, chorea, and retinal arterial thrombosis along with laboratory evidence of autoimmunity. In the absence of systemic lupus erythematosus, the clinical manifestations suggest the presence of the primary antiphospholipid antibody syndrome.

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References

  1. Alarcón-Segovia D, Delezé M, Oria CV, Sánchez-Guerrero J, Gómez-Pacheco L, Cabiedes J, Fernández L, Ponce de León S (1989) Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus: a prospective analysis of 500 consecutive patients. Medicine (Baltimore) 68:353–365

    Google Scholar 

  2. Asherson RA, Hughes GR (1988) Antiphospholipid antibodies and chorea (Letter). J Rheumatol 15:377–379

    Google Scholar 

  3. Asherson RA, Khamashta MA, Gil A, Vazquez JJ, Chan O, Baguley E, Hughes GR (1989) Cerebrovascular disease and antiphospholipid antibodies in systemic lupus erythematosus, lupus-like disease, and the primary antiphospholipid syndrome. Am J Med 86:391–399

    Google Scholar 

  4. Asherson RA, Khamashta MA, Ordi-Ros J, Derksen RHWM, Machin SJ, Barquinero J, Outt HH, Harris EN, Vilardell-Torres M, Hughes GRV (1989) The “primary” antiphospholipid syndrome: major clinical and serological features. Medicine (Baltimore) 68:366–374

    Google Scholar 

  5. Briley DP, Coull BM, Goodnight SH Jr (1989) Neurological disease associated with antiphospholipid antibodies. Ann Neurol 25:221–227

    Google Scholar 

  6. Headache Classification Committee of the International Headache Society (1988) Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalalgia 8 [Suppl 7]:1–96

    Google Scholar 

  7. Hodges JR (1987) Chorea and the lupus anticoagulant (Letter). J Neurol Neurosurg Psychiatry 50:368–369

    Google Scholar 

  8. Hogan MJ, Brunet DG, Ford PM, Lillicrap D (1988) Lupus anticoagulant, antiphospholipid antibodies and migraine. Can J Neurol Sci 15:420–425

    Google Scholar 

  9. Jonas J, Kölble K, Völcker HE, Kalden JR (1986) Central retinal artery occlusion in Sneddon's disease associated with antiphospholipid antibodies. Am J Ophthalmol 102:37–40

    Google Scholar 

  10. Levine SR, Welch KM (1987) Cerebrovascular ischemia associated with lupus anticoagulant. Stroke 18:257–263

    Google Scholar 

  11. Levine SR, Welch KMA (1989) Antiphospholipid antibodies. Ann Neurol 26:386–389

    Google Scholar 

  12. Levine SR, Joseph R, D'Andrea G, Welch KM (1987) Migraine and the lupus anticoagulant: case reports and review of the literature. Cephalalgia 7:93–99

    Google Scholar 

  13. Meyer O, Piette JC, Bourgeois P, Fallas P, Bletry O, Jungers P, Kahn MF, Godeau P, Ryckewaert A (1987) Antiphospholipid antibodies: a disease marker in 25 patients with antinuclear antibody negative systemic lupus erythematosus (SLE): comparison with a group of 91 patients with antinuclear antibody positive SLE. J Rheumatol 14:502–506

    Google Scholar 

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Author notes

  1. M. J. Stillman

    Present address: The Polyclinic, 1145 Broadway, 98122-4299, Seattle, WA, USA

Authors and Affiliations

  1. Department of Neurology, Lahey Clinic Medical Center, 41 Mall Road, 01805, Burlington, MA, USA

    J. A. Gutrecht & M. J. Stillman

  2. Section of Rheumatology, Lahey Clinic Medical Center, 41 Mall Road, 01805, Burlington, MA, USA

    N. Kattwinkel

Authors
  1. J. A. Gutrecht
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  2. N. Kattwinkel
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  3. M. J. Stillman
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Gutrecht, J.A., Kattwinkel, N. & Stillman, M.J. Retinal migraine, chorea, and retinal artery thrombosis in a patient with primary antiphospholipid antibody syndrome. J Neurol 238, 55–56 (1991). https://doi.org/10.1007/BF00319714

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  • DOI: https://doi.org/10.1007/BF00319714

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