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DNA probe localization at 18p113 band by in situ hybridization and identification of a small supernumerary chromosome

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Summary

Recombinant plasmid clone B74 (also named D18S3) containing a human single-copy DNA segment of 6 kilobases (kb) was localized by in situ hybridization on band p113 of chromosome 18. This probe was then used in cytogenetic diagnosis to identify precisely a small supernumerary chromosome as an isochromosome i(18p).

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Mattei, M.G., Philip, N., Passage, E. et al. DNA probe localization at 18p113 band by in situ hybridization and identification of a small supernumerary chromosome. Hum Genet 69, 268–271 (1985). https://doi.org/10.1007/BF00293038

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  • DOI: https://doi.org/10.1007/BF00293038

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