Literatur
Alpen, E. L., H. G. Mandel, V. W. Rodwell and P. K. Smith: The metabolism of C14 carboxyl salicylic acid in the dog and in man. J. Pharmacol. exp. Ther. 102, 150 (1951).
Baer, J. E., S. F. Paulson, H. F. Russo and K. H. Beyer: Renal elimination of 3-methylaminoisocamphane hydrochloride (mecamylamine). Amer. J. Physiol. 186, 180 (1956).
Beyer, K. H., H. F. Russo, E. A. Patch, L. Peters and K. L. Sprague: The formation and excretion of acetylated sulfonamides. J. Lab. clin. Med. 31, 65 (1946).
Bratton, A. C., and E. K. Marshall jr.: A new coupling component for sulfonamide determination. J. Brit. Chem. 128, 537 (1939).
Braun, W., u. H. Schniewind: Die Anreicherung von Probenecid (35S) in Nierenschnitten des Meerschweinchens. Naunyn-Schmiedeberg's Arch. exp. Path. Pharmak. 243, 429 (1962).
Brodie, B. B., J. J. Burns, L. M. Mark, P. A. Lief, E. Bernstein and E. M. Papper: The fate of pentobarbital in man and dog and a method for its estimation in biological material. J. Pharmacol. exp. Ther. 109, 26 (1953).
Bünger, P., u. G. Koch: Klinische Untersuchungen mit 2-Sulfanilamido-5-methoxypyrimidin. Arzneimittel-Forsch. 11, 726 (1961).
Chambers, R., and R. Kempton: Elimination of neutralred by frog's kidney. J. cell. comp. Physiol. 10, 199 (1937).
Cross, R. I., and J. V. Taggart: Renal tubular transport: Accumulation of p-aminohippurate by rabbit kidney slices. Amer. J. Physiol. 161, 181 (1950).
Dalgaard-Mikkelson, S.: On the renal excretion of salicylate. Acta pharmacol. (Kbh.) 7, 243 (1951).
Davis, P. L., and P. K. Smith: Relation of rate of excretion of salicylate to urinary acidity. Arch. int. Pharmacodyn. 86, 303 (1951).
Despopoulos, A., and P. X. Callahan: Molecular features of sulfonamide transport in renal excretory processes. Amer. J. Physiol. 203, 19 (1962).
Forster, R. P.: Use of thin kidney slices and isolated renal tubules for direct study of cellular transport kinetics. Science 108, 65 (1948).
Gutman, A. B., T. F. Yü and J. H. Sirota: A study, by simultaneous clearance techniques, of salicylate excretion in man. Effect of alkalinization of the urine by bicarbonate administration; effect of probenecid. J. clin. Invest. 34, 711 (1955).
Haag, H. B., and P. S. Larson: Studies on the fate of nicotine in the body. 1. The effect of pH on the urinary excretion of nicotine by tobacco smokers. J. Pharmacol. exp. Ther. 76, 235 (1942).
: The effect of urinary pH on the elimination of quinine in man. J. Pharmacol. exp. Ther. 79, 136 (1943).
Heidenreich, O., H. U. May u. Y. Kook: Die Resorption von Inulin und Paraaminohippursäure in Ureter und Blase bei kleinen Harnflüssen. Klin. Wschr. 39, 302 (1961).
Höber, R.: Physikalische Chemie der Zellen und Gewebe. Bern: Stämpfli & Co. 1947.
Jailer, J. W., M. Rosenfeld and J. A. Shannon: The influence of orally administered alkali and acid on the renal excretion of quinacrine, chloroquine and santoquine. J. clin. Invest. 26, 1168 (1947).
Jenson, R. L., G. J. Tobias, J. F. Greaney, A. S. Relman and W. B. Schwartz: Renal tubular function during severe metabolic acidosis. Amer. J. Physiol. 179, 188 (1954).
Kostenbauder, H. B., J. B. Portnoff and J. V. Swintosky: Control of urine pH and its effect on sulfaethidole excretion in humans. J. pharm. Sci. 51, 1084 (1962).
Lee Rodkey, F.: The binding of phenolred by serum and by bovine serum albumin. Arch. Biochem. 94, 38 (1961).
Lew, H. S., E. C. Lee, K. S. Lee and S. K. Hong: Urinary and biliary excretion of dyes in acidosis and alkalosis in the dog. Amer. J. Physiol. 203, 644 (1962).
MacPherson, C. R., M. D. Milne and B. M. Evans: The excretion of salicylate. Brit. J. Pharmacol. 10, 150 (1951).
Maggioni, G. F.: Some observations on salicylate therapy in children. Biochem. J. 41 (1947).
Milne, M. D., M. A. Crawford, C. B. Girâo and L. Loughridge: The excretion of indolyacetic acids in man and the rat. Clin. Sci. 19, 165 (1962).
: Non-ionic diffusion and the excretion of weak acids and bases. Amer. J. Med. 24, 709 (1958).
Mollaret, P., M. Rapin, J. F. Monsallier et J. J. Pocidalo: Etudes sur l'intoxication barbiturique aiguë. II. Action de l'alcalose urinaire sur l'élimation rénale du phénobarbital chez la chien. Rev. franç. Etud. clin. biol. 4, 661 (1959).
: Le traitement de l'intoxication barbiturique aiguë. Presse méd. 67, 1435 (1959).
Newbould, B. B., and R. Kilpatrick: Long acting sulphonamides and proteinbinding. Lancet 1960 I, 887.
Orloff, J., and R. W. Berliner: The mechanism of the excretion of ammonia in the dog. J. clin. Invest. 35, 223 (1956).
Osterhout, J. V.: Is living protoplasma permeable to ions? J. gen. Physiol. 8, 131 (1925).
Overton, E.: Über die osmotischen Eigenschaften der Zelle in ihrer Bedeutung für die Toxikologie und Pharmakologie. Z. physik. Chem. 22, 189 (1897).
Parker, W. A.: Factors influencing plasma concentrations of salicylate. Quart. J. Med. 17, 229 (1948).
Peters, L.: Renal tubular excretion of organic bases. Pharmacol. Rev. 12, 1 (1960).
Peterson, O. L., and M. Finland: Effect of food and alkali on absorption and excretion of sulfonamide drugs after oral and duodenal administration. Amer. J. med. Sci. 204, 581 (1942).
Popperl, H., E. Mandel u. H. Mayer: Zur Kreatininbestimmung im Blute. Biochem. Z. 291, 354 (1937).
Rector, F. C., D. W. Seldin and J. H. Copenhaver: The mechanism of ammonia excretion during ammonium chloride acidosis. J. clin. Invest. 34, 20 (1955).
: Relation of ammonia excretion to urine pH. Amer. J. Physiol. 179, 353 (1954).
Richterich, R.: Physico-chemical factors determining ammonia excretion. Helv. physiol. pharmacol. Acta 20, 326 (1962).
Sandler, M., and R. G. Spector: Effect of urinary pH on 5-hydroxytryptamine excretion in the rat. Nature (Lond.) 189, 838 (1961).
Schachter, D., and N. Freinkel: Self depression of T m PAH in the dog at high plasma PAH levels and its reversibility by acetat. Amer. J. Physiol. 167, 531 (1951).
Schachter, D., and J. G. Manis: Salicylate and salicyl conjugates: Fluorimetric estimation, biosynthesis and renal excretion in man. J. clin. Invest. 37, 800 (1958).
Scribner, B. H., M. A. Crawford and W. J. Dempster: Urinary excretion by non-ionic diffusion. Amer. J. Physiol. 196, 1135 (1959).
Smith, P. K.: Certain aspects of the pharmacology of the salicylates. Pharmacol. Rev. 1, 353 (1949).
: Studies on the pharmacology of salicylates. J. Pharmacol. exp. Ther. 87, 237 (1946).
Smull, K., R. Wégria and J. Leland: The effect of sodium bicarbonate on the serum salicylate level during salicylate therapy of patients with acute rheumatic fever. J. Amer. med. Ass. 125, 1173 (1944).
Sperber, I.: A new method for the study of renal tubular excretion in birds. Nature (Lond.) 158, Nr. 4004 (1946).
Competitiv inhibition and specificity of renal tubular transport mechanisms. Arch. int. Pharmacodyn. 97, 221 (1954).
Thompson, H. E., and C. A. Dragstedt: Modifying action of calcium and sodium bicarbonate on salicylate intoxication. Arch. intern. Med. 54, 308 (1934).
Waddell, J., and T. C. Buttler: The distribution and excretion of phenobarbital. J. clin. Invest. 36, 1217 (1957).
Weiner, I. M., K. D. Garlid, J. A. Romeo and G. H. Mudge: Effects of tubular secretion and reabsorption on titration curves of tubular transport. Amer. J. Physiol. 200, 393 (1961).
: Studies on the renal excretion of salicylate in the dog. Bull. Johns Hopk. Hosp. 105, 284 (1959).
On the mechanism of action of probenecid on renal tubular secretion. Bull. Johns Hopk. Hosp. 106, 333 (1960).
Williams, F., and J. R. Leonards: The effect of sodium bicarbonate on the renal excretion of salicylate. J. Pharmacol. exp. Ther. 93, 401 (1948).
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Braun, W., Hesse, I. & Malorny, G. Zur Bedeutung pH-abhängiger Diffusionsvorgänge für die Nierenfunktion. Naunyn-Schmiedebergs Arch 245, 457–470 (1963). https://doi.org/10.1007/BF00259331
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DOI: https://doi.org/10.1007/BF00259331