Skip to main content
Log in

Zur Bedeutung pH-abhängiger Diffusionsvorgänge für die Nierenfunktion

  • Published:
Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  • Alpen, E. L., H. G. Mandel, V. W. Rodwell and P. K. Smith: The metabolism of C14 carboxyl salicylic acid in the dog and in man. J. Pharmacol. exp. Ther. 102, 150 (1951).

    Google Scholar 

  • Baer, J. E., S. F. Paulson, H. F. Russo and K. H. Beyer: Renal elimination of 3-methylaminoisocamphane hydrochloride (mecamylamine). Amer. J. Physiol. 186, 180 (1956).

    Google Scholar 

  • Beyer, K. H., H. F. Russo, E. A. Patch, L. Peters and K. L. Sprague: The formation and excretion of acetylated sulfonamides. J. Lab. clin. Med. 31, 65 (1946).

    Google Scholar 

  • Bratton, A. C., and E. K. Marshall jr.: A new coupling component for sulfonamide determination. J. Brit. Chem. 128, 537 (1939).

    Google Scholar 

  • Braun, W., u. H. Schniewind: Die Anreicherung von Probenecid (35S) in Nierenschnitten des Meerschweinchens. Naunyn-Schmiedeberg's Arch. exp. Path. Pharmak. 243, 429 (1962).

    Google Scholar 

  • Brodie, B. B., J. J. Burns, L. M. Mark, P. A. Lief, E. Bernstein and E. M. Papper: The fate of pentobarbital in man and dog and a method for its estimation in biological material. J. Pharmacol. exp. Ther. 109, 26 (1953).

    Google Scholar 

  • Bünger, P., u. G. Koch: Klinische Untersuchungen mit 2-Sulfanilamido-5-methoxypyrimidin. Arzneimittel-Forsch. 11, 726 (1961).

    Google Scholar 

  • Chambers, R., and R. Kempton: Elimination of neutralred by frog's kidney. J. cell. comp. Physiol. 10, 199 (1937).

    Google Scholar 

  • Cross, R. I., and J. V. Taggart: Renal tubular transport: Accumulation of p-aminohippurate by rabbit kidney slices. Amer. J. Physiol. 161, 181 (1950).

    Google Scholar 

  • Dalgaard-Mikkelson, S.: On the renal excretion of salicylate. Acta pharmacol. (Kbh.) 7, 243 (1951).

    Google Scholar 

  • Davis, P. L., and P. K. Smith: Relation of rate of excretion of salicylate to urinary acidity. Arch. int. Pharmacodyn. 86, 303 (1951).

    Google Scholar 

  • Despopoulos, A., and P. X. Callahan: Molecular features of sulfonamide transport in renal excretory processes. Amer. J. Physiol. 203, 19 (1962).

    Google Scholar 

  • Forster, R. P.: Use of thin kidney slices and isolated renal tubules for direct study of cellular transport kinetics. Science 108, 65 (1948).

    Google Scholar 

  • Gutman, A. B., T. F. and J. H. Sirota: A study, by simultaneous clearance techniques, of salicylate excretion in man. Effect of alkalinization of the urine by bicarbonate administration; effect of probenecid. J. clin. Invest. 34, 711 (1955).

    Google Scholar 

  • Haag, H. B., and P. S. Larson: Studies on the fate of nicotine in the body. 1. The effect of pH on the urinary excretion of nicotine by tobacco smokers. J. Pharmacol. exp. Ther. 76, 235 (1942).

    Google Scholar 

  • : The effect of urinary pH on the elimination of quinine in man. J. Pharmacol. exp. Ther. 79, 136 (1943).

    Google Scholar 

  • Heidenreich, O., H. U. May u. Y. Kook: Die Resorption von Inulin und Paraaminohippursäure in Ureter und Blase bei kleinen Harnflüssen. Klin. Wschr. 39, 302 (1961).

    Google Scholar 

  • Höber, R.: Physikalische Chemie der Zellen und Gewebe. Bern: Stämpfli & Co. 1947.

    Google Scholar 

  • Jailer, J. W., M. Rosenfeld and J. A. Shannon: The influence of orally administered alkali and acid on the renal excretion of quinacrine, chloroquine and santoquine. J. clin. Invest. 26, 1168 (1947).

    Google Scholar 

  • Jenson, R. L., G. J. Tobias, J. F. Greaney, A. S. Relman and W. B. Schwartz: Renal tubular function during severe metabolic acidosis. Amer. J. Physiol. 179, 188 (1954).

    Google Scholar 

  • Kostenbauder, H. B., J. B. Portnoff and J. V. Swintosky: Control of urine pH and its effect on sulfaethidole excretion in humans. J. pharm. Sci. 51, 1084 (1962).

    Google Scholar 

  • Lee Rodkey, F.: The binding of phenolred by serum and by bovine serum albumin. Arch. Biochem. 94, 38 (1961).

    Google Scholar 

  • Lew, H. S., E. C. Lee, K. S. Lee and S. K. Hong: Urinary and biliary excretion of dyes in acidosis and alkalosis in the dog. Amer. J. Physiol. 203, 644 (1962).

    Google Scholar 

  • MacPherson, C. R., M. D. Milne and B. M. Evans: The excretion of salicylate. Brit. J. Pharmacol. 10, 150 (1951).

    Google Scholar 

  • Maggioni, G. F.: Some observations on salicylate therapy in children. Biochem. J. 41 (1947).

  • Milne, M. D., M. A. Crawford, C. B. Girâo and L. Loughridge: The excretion of indolyacetic acids in man and the rat. Clin. Sci. 19, 165 (1962).

    Google Scholar 

  • : Non-ionic diffusion and the excretion of weak acids and bases. Amer. J. Med. 24, 709 (1958).

    Google Scholar 

  • Mollaret, P., M. Rapin, J. F. Monsallier et J. J. Pocidalo: Etudes sur l'intoxication barbiturique aiguë. II. Action de l'alcalose urinaire sur l'élimation rénale du phénobarbital chez la chien. Rev. franç. Etud. clin. biol. 4, 661 (1959).

    Google Scholar 

  • : Le traitement de l'intoxication barbiturique aiguë. Presse méd. 67, 1435 (1959).

    Google Scholar 

  • Newbould, B. B., and R. Kilpatrick: Long acting sulphonamides and proteinbinding. Lancet 1960 I, 887.

    Google Scholar 

  • Orloff, J., and R. W. Berliner: The mechanism of the excretion of ammonia in the dog. J. clin. Invest. 35, 223 (1956).

    Google Scholar 

  • Osterhout, J. V.: Is living protoplasma permeable to ions? J. gen. Physiol. 8, 131 (1925).

    Google Scholar 

  • Overton, E.: Über die osmotischen Eigenschaften der Zelle in ihrer Bedeutung für die Toxikologie und Pharmakologie. Z. physik. Chem. 22, 189 (1897).

    Google Scholar 

  • Parker, W. A.: Factors influencing plasma concentrations of salicylate. Quart. J. Med. 17, 229 (1948).

    Google Scholar 

  • Peters, L.: Renal tubular excretion of organic bases. Pharmacol. Rev. 12, 1 (1960).

    Google Scholar 

  • Peterson, O. L., and M. Finland: Effect of food and alkali on absorption and excretion of sulfonamide drugs after oral and duodenal administration. Amer. J. med. Sci. 204, 581 (1942).

    Google Scholar 

  • Popperl, H., E. Mandel u. H. Mayer: Zur Kreatininbestimmung im Blute. Biochem. Z. 291, 354 (1937).

    Google Scholar 

  • Rector, F. C., D. W. Seldin and J. H. Copenhaver: The mechanism of ammonia excretion during ammonium chloride acidosis. J. clin. Invest. 34, 20 (1955).

    Google Scholar 

  • : Relation of ammonia excretion to urine pH. Amer. J. Physiol. 179, 353 (1954).

    Google Scholar 

  • Richterich, R.: Physico-chemical factors determining ammonia excretion. Helv. physiol. pharmacol. Acta 20, 326 (1962).

    Google Scholar 

  • Sandler, M., and R. G. Spector: Effect of urinary pH on 5-hydroxytryptamine excretion in the rat. Nature (Lond.) 189, 838 (1961).

    Google Scholar 

  • Schachter, D., and N. Freinkel: Self depression of T m PAH in the dog at high plasma PAH levels and its reversibility by acetat. Amer. J. Physiol. 167, 531 (1951).

    Google Scholar 

  • Schachter, D., and J. G. Manis: Salicylate and salicyl conjugates: Fluorimetric estimation, biosynthesis and renal excretion in man. J. clin. Invest. 37, 800 (1958).

    Google Scholar 

  • Scribner, B. H., M. A. Crawford and W. J. Dempster: Urinary excretion by non-ionic diffusion. Amer. J. Physiol. 196, 1135 (1959).

    Google Scholar 

  • Smith, P. K.: Certain aspects of the pharmacology of the salicylates. Pharmacol. Rev. 1, 353 (1949).

    Google Scholar 

  • : Studies on the pharmacology of salicylates. J. Pharmacol. exp. Ther. 87, 237 (1946).

    Google Scholar 

  • Smull, K., R. Wégria and J. Leland: The effect of sodium bicarbonate on the serum salicylate level during salicylate therapy of patients with acute rheumatic fever. J. Amer. med. Ass. 125, 1173 (1944).

    Google Scholar 

  • Sperber, I.: A new method for the study of renal tubular excretion in birds. Nature (Lond.) 158, Nr. 4004 (1946).

    Google Scholar 

  • Competitiv inhibition and specificity of renal tubular transport mechanisms. Arch. int. Pharmacodyn. 97, 221 (1954).

    Google Scholar 

  • Thompson, H. E., and C. A. Dragstedt: Modifying action of calcium and sodium bicarbonate on salicylate intoxication. Arch. intern. Med. 54, 308 (1934).

    Google Scholar 

  • Waddell, J., and T. C. Buttler: The distribution and excretion of phenobarbital. J. clin. Invest. 36, 1217 (1957).

    Google Scholar 

  • Weiner, I. M., K. D. Garlid, J. A. Romeo and G. H. Mudge: Effects of tubular secretion and reabsorption on titration curves of tubular transport. Amer. J. Physiol. 200, 393 (1961).

    Google Scholar 

  • : Studies on the renal excretion of salicylate in the dog. Bull. Johns Hopk. Hosp. 105, 284 (1959).

    Google Scholar 

  • On the mechanism of action of probenecid on renal tubular secretion. Bull. Johns Hopk. Hosp. 106, 333 (1960).

    Google Scholar 

  • Williams, F., and J. R. Leonards: The effect of sodium bicarbonate on the renal excretion of salicylate. J. Pharmacol. exp. Ther. 93, 401 (1948).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Mit 5 Textabbildungen

Mit Unterstützung der Deutschen Forschungsgemeinschaft.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Braun, W., Hesse, I. & Malorny, G. Zur Bedeutung pH-abhängiger Diffusionsvorgänge für die Nierenfunktion. Naunyn-Schmiedebergs Arch 245, 457–470 (1963). https://doi.org/10.1007/BF00259331

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00259331

Navigation