Abstract
The distribution of the 2000 copies of the Y-specific repetitive family DYZ2 is controversial since previous reports have mapped these sequences to different sites of the Yqh region. In this work, we have performed non-radioactive in situ hybridization of a cloned DYZ2 fragment at higher stringency conditions on 5-aza-cytidine-enlarged Y chromosomes; the results suggest a non-uniform distribution of these sequences, which are preferentially located at the proximal and distal parts of Yqh, including the C+/Q-heterochromatin at the boundary with the euchromatic region.
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Ludeña, P., Fernández-Piqueras, J. & Sentís, C. Distribution of DYZ2 repetitive sequences on the human Y chromosome. Hum Genet 90, 572–574 (1993). https://doi.org/10.1007/BF00217462
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DOI: https://doi.org/10.1007/BF00217462