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Effect of cerulenin on the production of mannosyl-erythritol lipids as biosurfactants by Candida antarctica

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Summary

The effect of cerulenin, anti-lipogenic antibiotic, on the production and fatty-acid profiles of biosurfactants (mannosyl-erythritol lipids) of Candida antarctica were investigated by changing the chain-length of fatty acid as the carbon source. On longer-chain acid (C14 to C18), the production and fatty-acid profiles of the biosurfactants were not entirely affected by the antibiotic, indicating that the yeast is able to synthesize the biosurfactants from those substrates without the operation of “de novo synthesis system” of fatty acid. These results thus confirm our previous presumption that a new type of “chain-shortening system” (partial β-oxidation system) mainly contributes to the formation of the extracellular glycolipids as biosurfactants.

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Authors and Affiliations

  1. National Institute of Materials and Chemical Research, Tsukuba, 305, Ibaraki, Japan

    Daï Kitamoto, Hiroshi Yanagishita & Kenji Haraya

  2. National Grassland Research Institute, Nishinasuno, 329-27, Tochigi, Japan

    Hiroko K. Kitamoto

Authors
  1. Daï Kitamoto
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  2. Hiroshi Yanagishita
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  3. Kenji Haraya
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  4. Hiroko K. Kitamoto
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Kitamoto, D., Yanagishita, H., Haraya, K. et al. Effect of cerulenin on the production of mannosyl-erythritol lipids as biosurfactants by Candida antarctica . Biotechnol Lett 17, 25–30 (1995). https://doi.org/10.1007/BF00134190

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  • DOI: https://doi.org/10.1007/BF00134190

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