Abstract
Peroxisomes are single-membrane bound intracellular organelles that can be found in organisms across the tree of eukaryotes, and thus are likely to derive from an ancestral peroxisome in the last eukaryotic common ancestor (LECA). Yet, peroxisomes in different lineages can present a large diversity in terms of their metabolic capabilities, which reflects a highly variable proteomic content. Theories on the evolutionary origin of peroxisomes have shifted in the last decades from scenarios involving an endosymbiotic origin, similar to those of mitochondria and plastids, towards hypotheses purporting an endogenous origin from within the endomembrane system. The peroxisomal proteome is highly dynamic in evolutionary terms, and can evolve via differential loss and gain of proteins, as well as via relocalization of proteins from and to other sub-cellular compartments. Here, I review current knowledge and discussions on the diversity, origin, and evolution of the peroxisomal proteome.
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Abbreviations
- LECA:
-
Last eukaryotic common ancestor
- H2O2:
-
Hydrogen peroxide
- PEX:
-
Peroxin
- ER:
-
Endoplasmic reticulum
- ERAD:
-
Endoplasmic reticulum associated decay
- AGT:
-
Alanine:glyoxylate aminotransferase
- PXA:
-
Peroxisomal ABC transporter
- CTA:
-
Catalase
- FOX:
-
Fatty acid oxidase
- FAA:
-
Fatty acid CoA synthetase
References
Andersen JS, Mann M (2006) Organellar proteomics: turning inventories into insights. EMBO Reports 874–879. https://doi.org/10.1038/sj.embor.7400780
Antonenkov VD, Hiltunen JK (2012) Transfer of metabolites across the peroxisomal membrane. Biochim Biophys Acta Mol Basis Dis 1374–1386. https://doi.org/10.1016/j.bbadis.2011.12.011
Bowers WE (1998) Christian de Duve and the discovery of lysosomes and peroxisomes. Trends in Cell Biol 330–333. https://doi.org/10.1016/s0962-8924(98)01314-2
Breidenbach RW, Kahn A, Beevers H (1968) Characterization of glyoxysomes from castor bean endosperm. Plant Physiol 43(5):705–713. https://doi.org/10.1104/PP.43.5.705
Cooper TG, Beevers H (1969) Beta oxidation in glyoxysomes from castor bean endosperm. J Biol Chem 244(13):3514–3520
de Duve C (1982) Peroxisomes and related particles in historical perspective. Ann NY Acad Sci 386(1):1–4. https://doi.org/10.1111/j.1749-6632.1982.tb21402.x
De Duve C (1996) ‘The peroxisome in retrospect. Ann NY Acad Sci 1–10. https://doi.org/10.1111/j.1749-6632.1996.tb18603.x
De Duve C (2007) The origin of eukaryotes: a reappraisal. Nat Rev Genet 395–403. https://doi.org/10.1038/nrg2071
De Duve C, Baudhuin P (1966) Peroxisomes (microbodies and related particles). Physiol Rev 46(2):323–357
Erdmann R, Schliebs W (2005) Peroxisomal matrix protein import: the transient pore model. Nat Rev Mol Cell Biol 738–742. https://doi.org/10.1038/nrm1710
Gabaldón T et al (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 8. https://doi.org/10.1186/1745-6150-1-8
Gabaldón T (2010) Peroxisome diversity and evolution. Philosophical Trans Royal Soc Lond Ser B: Biol Sci 365(1541):765–773. Available at: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20124343
Gabaldón T (2014a) A metabolic scenario for the evolutionary origin of peroxisomes from the endomembranous system. Cell Mol Life Sci 71(13):2373–2376. https://doi.org/10.1007/s00018-013-1424-z
Gabaldón T (2014b) Evolutionary considerations on the origin of peroxisomes from the endoplasmic reticulum, and their relationships with mitochondria. Cell Mol Life Sci 2379–2382. https://doi.org/10.1007/s00018-014-1640-1
Gabaldón T, Ginger ML, Michels PAM (2016) Peroxisomes in parasitic protists. Mol Biochem Parasitol 209(1–2):35–45. https://doi.org/10.1016/j.molbiopara.2016.02.005
Gabaldón T, Pittis AA (2015) Origin and evolution of metabolic sub-cellular compartmentalization in eukaryotes. Biochimie 119:262–268. https://doi.org/10.1016/j.biochi.2015.03.021
Gualdrón-López M et al (2012) When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle. Int J Parasitol 1–20. https://doi.org/10.1016/j.ijpara.2011.10.007
Holland HD et al (2006) The oxygenation of the atmosphere and oceans. Philos Trans R Soc Lond B Biol Sci 361(1470):903–915. https://doi.org/10.1098/rstb.2006.1838
Jedd G, Chua NH (2000) A new self-assembled peroxisomal vesicle required for efficient resealing of the plasma membrane. Nat Cell Biol 2(4):226–231. https://doi.org/10.1038/35008652
Lazarow PB, De Duve C (1976) A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug. Proc Natl Acad Sci USA 73(6):2043–2046. https://doi.org/10.1073/pnas.73.6.2043
Ludewig-Klingner A-K et al (2018) Distribution and evolution of peroxisomes in alveolates (apicomplexa, dinoflagellates, ciliates). Genome Biol Evol 10(1):1–13. https://doi.org/10.1093/gbe/evx250
Opperdoes FR, Borst P (1977) Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei: the glycosome. FEBS Lett 80(2):360–364. https://doi.org/10.1016/0014-5793(77)80476-6
Pieuchot L, Jedd G (2012) Peroxisome assembly and functional diversity in eukaryotic microorganisms. Annu Rev Microbiol 66(1):237–263. https://doi.org/10.1146/annurev-micro-092611-150126
Rhodin JAG (1954) Correlation of ultrastructural organization : and function in normal and experimentally changed proximal convoluted tubule cells of the mouse kidney: an electron microscopic study. Department of Anatomy, Karolinska Institute, Solna
Schlüter A et al (2006) The evolutionary origin of peroxisomes: an ER-peroxisome connection. Mol Biol Evol 23(4):838–845. https://doi.org/10.1093/molbev/msj103
Schlüter A et al (2007) PeroxisomeDB: a database for the peroxisomal proteome, functional genomics and disease. Nucleic Acids Res. Oxford University Press 35(Database issue) D815–D822. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1747181&tool=pmcentrez&rendertype=abstract
Smith JJ, Aitchison JD (2013) Peroxisomes take shape. Nat Rev Mol Cell Biol 803–817. https://doi.org/10.1038/nrm3700
Speijer D (2011) Oxygen radicals shaping evolution: why fatty acid catabolism leads to peroxisomes while neurons do without it. BioEssays 33(2):88–94. https://doi.org/10.1002/bies.201000097
Speijer D (2017) Evolution of peroxisomes illustrates symbiogenesis. BioEssays 39(9). https://doi.org/10.1002/bies.201700050
Szabo AS, Avers CJ (1969) Some aspects of regulation of peroxisomes and mitochondria in yeast. Ann NY Acad Sci 168(2):302–312. https://doi.org/10.1111/j.1749-6632.1969.tb43117.x
Szöör B et al (2014) Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids. Curr Opin Microbiol 79–87. https://doi.org/10.1016/j.mib.2014.09.006
Tabak HF et al (2003) Peroxisomes start their life in the endoplasmic reticulum. Traffic (Copenhagen, Denmark) 4(8):512–518. doi:110 [pii]
Taylor SW, Fahy E, Ghosh SS (2003) Global organellar proteomics. Trends in Biotechnol 82–88. https://doi.org/10.1016/s0167-7799(02)00037-9
Terlecky SR et al (2009) The role of peroxisomes in the regulation of Podospora anserina sexual development. Res Signpost 37661(2):61–85
Tolbert NE et al (1968) Peroxisomes from spinach leaves containing enzymes related to glycolate metabolism. J Biol Chem 243(19):5179–5184
van der Klei IJ, Veenhuis M (2013) The versatility of peroxisome function in filamentous fungi. Subcell Biochem 69:135–152. https://doi.org/10.1007/978-94-007-6889-5_8
Acknowledgements
TG acknowledges support of the Spanish Ministry of Economy and Competitiveness grants, ‘Centro de Excelencia Severo Ochoa 2013-2017’ SEV-2012-0208, and BFU2015-67107 cofounded by European Regional Development Fund (ERDF); from the CERCA Programme/Generalitat de Catalunya; from the Catalan Research Agency (AGAUR) SGR857, and grants from the European Union’s Horizon 2020 research and innovation programme under the grant agreement ERC-2016-724173 and the Marie Sklodowska-Curie grant agreement No H2020-MSCA-ITN-642095.
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Gabaldón, T. (2018). Evolution of the Peroxisomal Proteome. In: del Río, L., Schrader, M. (eds) Proteomics of Peroxisomes. Subcellular Biochemistry, vol 89. Springer, Singapore. https://doi.org/10.1007/978-981-13-2233-4_9
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