Skip to main content
SpringerLink
Log in
Book cover
  • Book
  • © 2017

Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin

Methodology and General Considerations

Editors:

  1. Nina Dragicevic

    1. Apoteka “Beograd”, Belgrade, Serbia

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Howard I. Maibach

    1. San Francisco, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • The most comprehensive reference on enhancement methods in the field of dermal/transdermal drug delivery, now in a mini-series format with five volumes Thorough description of both the best known and the most recently developed chemical and physical methods

  • Edited by a team of the most experienced scientists in the field

  • Invaluable for researchers, pharmaceutical scientists, practitioners, and students?

Sections

Buy it now

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (24 chapters)

  1. Front Matter

    Pages i-xvi
    PDF

  2. Factors Influencing Percutaneous Drug Penetration

    1. Front Matter

      Pages 1-1
      PDF

    2. Basic Mathematics in Skin Absorption

      • Dominik Selzer, Ulrich F. Schaefer, Claus-Michael Lehr, Steffi Hansen
      Pages 3-25

    4. Finite and Infinite Dosing

      • Wing Man Lau, Keng Wooi Ng
      Pages 35-44

    5. Non-formulation Parameters That Affect Penetrant-Skin-Vehicle Interactions and Percutaneous Absorption

      • Jeffrey E. Grice, Hamid R. Moghimi, Elizabeth Ryan, Qian Zhang, Isha Haridass, Yousuf Mohammed et al.
      Pages 45-75

    6. The Influence of Emollients on Dermal and Transdermal Drug Delivery

      • V. R. Leite-Silva, Jeffrey E. Grice, Yousuf Mohammed, Hamid R. Moghimi, Michael S. Roberts
      Pages 77-93

    8. Mechanistic Studies of Permeation Enhancers

      • S. Kevin Li, William I. Higuchi
      Pages 119-136

  3. Methods for Measuring the Percutaneous Drug Penetration

    1. Front Matter

      Pages 151-151
      PDF

    2. Models, Methods, and Measurements in Transdermal Drug Delivery

      • Donald M. Cropek, Pankaj Karande
      Pages 153-184

    3. Human Native and Reconstructed Skin Preparations for In Vitro Penetration and Permeation Studies

      • Ulrich F. Schaefer, D. Selzer, S. Hansen, Claus-Michael Lehr
      Pages 185-203

    4. Stripping Procedures for Penetration Measurements of Topically Applied Substances

      • Jürgen Lademann, Sabine Schanzer, Heike Richter, Martina C. Meinke, Hans-Jürgen Weigmann, Alexa Patzelt
      Pages 205-214

    6. Confocal Raman Spectroscopy as a Tool to Investigate the Action of Penetration Enhancers Inside the Skin

      • Stéphanie Briançon, Marie-Alexandrine Bolzinger, Yves Chevalier
      Pages 229-246

    7. ATR-FTIR Spectroscopy and the Skin Barrier: Evaluation of Penetration-Enhancement Effects

      • Julia Covi-Schwarz, Victoria Klang, Claudia Valenta
      Pages 247-254

    8. Confocal Microscopy for Visualization of Skin Penetration

      • Mukul A. Ashtikar, Daya D. Verma, Alfred Fahr
      Pages 255-281

    10. Corneoxenometry: A Bioassay Exploring Skin Barrier Breaching

      • Claudine Piérard-Franchimont, Trinh Hermanns-Lê, Gérald E. Piérard
      Pages 303-307
Back to top

About this book

Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists​.
Back to top

Keywords

Back to top

Editors and Affiliations

  • Apoteka “Beograd”, Belgrade, Serbia

    Nina Dragicevic

  • San Francisco, USA

    Howard I. Maibach

Back to top

About the editors

Howard I. Maibach is Professor of Dermatology at the University of California, San Francisco. He is a leading authority in the fields of dermatotoxicology and dermatopharmacology, in which he has conducted much original research and written very extensively, with a total of more than 2,500 publications as lead or co-author. Professor Maibach has served on the editorial boards of more than 30 scientific journals and is a member of many professional societies, including the American Academy of Dermatology and the International Commission on Occupational Health. He has also been the recipient of numerous honors, both within the United States and overseas. Nina Dragićević-Ćurić graduated from the University of Belgrade, Faculty of Pharmacy in 1999 and subsequently obtained an MSc and a PhD (summa cum laude, Dr. rer. nat.) in Pharmaceutical Technology from the University of Belgrade and the Friedrich-Schiller University, Jena, respectively. Dr. Dragićević-Ćurić is an accredited Specialist in Pharmaceutical Technology. Since 2007 she has been responsible for the preparation of compounded drugs in pharmacies of the state pharmaceutical company “Apoteka Beograd” in Belgrade. She has published in a variety of international journals.
Back to top

Bibliographic Information

  • Book Title: Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin

  • Book Subtitle: Methodology and General Considerations

  • Editors: Nina Dragicevic, Howard I. Maibach

  • DOI: https://doi.org/10.1007/978-3-662-53270-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2017

  • Hardcover ISBN: 978-3-662-53268-3Published: 12 May 2017

  • Softcover ISBN: 978-3-662-57123-1Published: 11 September 2018

  • eBook ISBN: 978-3-662-53270-6Published: 04 May 2017

  • Edition Number: 1

  • Number of Pages: XVI, 414

  • Number of Illustrations: 76 b/w illustrations, 50 illustrations in colour

  • Topics: Dermatology, Pharmacology/Toxicology

Back to top

Publish with us

Policies and ethics

Back to top
Access via your institution

Buy it now

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Search

Navigation