Abstract
Different strategies of antimicrobial therapy in plant, human, and veterinary medicine have been developed to protect biological tissue from fungal infection and damage. The discovery of systemic fungicides has been an important advance in the development of new chemical therapies. Unlike protective, nonsystemic, and in most cases nonspecific compounds, systemic fungicides are characterized by mobility in plant tissue and selective activity against the pathogen at the infection site. The selectivity is based on structural and physiological differences between host and fungal parasite. For a comprehensive understanding of the mode of action of antifungal agents, biochemical and cellular aspects have to be taken into account. Electron microscopy can provide unique information concerning the influence of fungicides on the fine structure of the pathogen and host. The present review gives a current view of the ultrastructure research in the pharmacology of selectively acting agents.
Keywords
- Powdery Mildew
- Systemic Fungicide
- Melanin Biosynthesis
- Trichophyton Mentagrophytes
- Colletotrichum Lindemuthianum
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Barug D, Samson RA, Kerkenaar A (1983) Microscopic studies of Candida albicans and Torulopsis glabrata after in vitro treatment with bifonazole. Light and scanning electron microscopy. Drug Res 33: 528–537
Buchenauer H, Zeun R, Schinzer U (1985) Wirkung von Tricyclazol auf das Myzelwach-stum sowie die Entwicklung und Pigmentierung der Sklerotien von Sclerotinia sclerotiorum. Z Pflanzenkrankh Pflanzenschutz 92: 17–26
Cartwright DW, Langcake P, Ride JP (1980) Phytoalexin production in rice and its enhancement by a dichlorocyclopropane fungicide. Physiol Plant Pathol 17: 259–267
Casperson G, Lyr H (1982) Wirkung von Pentochlornitrobenzol (PCNB) auf die Ultrastruktur von Mucor mucedo und Phytophthora cactorum. Z Allg Mikrobiol 22: 219–226
Coffey MD, Young LH (1984) Responses to metalaxyl of sensitive and resistant isolates of Phytophthora infestans. Phytopathology 74: 615–620
Dahmen H, Hoch HC, Staub T (1988) Differential effects of sterol inhibitors on growth, cell membrane permeability, and ultrastructure of two target fungi. Phytopathology 78:1033–1042
Davidse LC (1986) Benzimidazole fungicides: mechanism of action and biological impact. Annu Rev Phytopathol 24: 43–65
Davidse LC (1987) Biochemical aspects of phenylamide fungicides—action and resistance. In: Lyr H (ed) Modern selective fungicides—properties, application, mechanisms of action, VEB Gustav Fischer Verlag Jena, Jena, pp 275
Grohmann U, Hoffmann GM (1982) Licht- und elektronenoptische Untersuchungen zur Wirkung von Metalaxyl bei Pythium- und Phytophthora Arten. Z Pflanzenkr Pflanzenschutz, 89:435–446
Heath IB (1982) The effect of nocodazole on the growth and ultrastructure of the fungus, Saprolegnia fer ax: evidence against a simple mode of action. In: Cappuccinelli P, Ronald Morris N (eds) Microtubules in microorganisms, Marcel Dekker, New York, pp 275
Heath MC (1988) Effect of fungal death or inhibition induced by oxycarboxin or polyoxin D on the interaction between resistant or susceptible bean cultivars and the bean rust fungus. Phytopathology 78: 1454–1462
Heller A, Frenzel B, Grossmann F, Hippe S (1990) Effects of ethirimol and propiconazole on morphology and ultrastructure of Erysiphe graminis f. sp. hordei Can J Botany 1990 (in press)
Hippe S, Buchenauer H, Grossmann F (1980) Einfluß von Triadimefon auf die Feinstruktur der Sporidien von Ustilago avenae. Z Pflanzenkr Pflanzenschutz 87: 423–426
Hippe S (1983) Morphology of Ustilago avenae after treatment with systemic fungicides as studied by scanning electron microscopy. Phytopathol Z 106: 321–328
Hippe S (1984) Electron microscopic investigations on the cytology of Ustilago avenae influenced by the systemic fungicides triadimefon, nuarimol and imazalil-nitrate: a thin-section and freeze-fracture study. Pestic Biochem Physiol 21: 170–183
Hippe S (1985) Hexagonal clustering of intramembrane particles in the plasmalemma of Ustilago avenae after fungicide treatment. Pestic Biochem Physiol 24: 161–173
Hippe S (1985) Ultrastructure of haustoria of Erysiphe graminis f.sp. hordei preserved by freeze-substitution. Protoplasma 129: 52–61
Hippe S Lüth H (1986) A simple physical model for fungicide induced hexagonal clustering of intramembrane particles in the plasmalemma of Ustilago avenae. J Theor Biol 21: 351–366
Hippe S (1987) Combined application of low temperature preparation and electron microscopic autoradiography for the localization of systemic fungicides. Histochemistry 87: 309–315
Hippe S, Giesen U (1988) The effect of triadimenol on the cytology and growth of sensitive and resistant strains of Ustilago avenae. Ann Appl Biol 112: 79–90
Hippe S Hermanns M (1988) Intracellular localization of the systemic fungicide triadimenol in phytopathogenic fungi. J Phytopathol 122: 13–24
Howard RJ, Aist JR (1980) Cytoplasmic microtubules and fungal morphogenesis: ultrastructural effects of methyl benzimidazole–2-ylcarbamate determined by freeze-substitution of hyphal tip cells. J Cell Biol 87: 55–64
Ishizaki H, Kohno M, Kunoh H (1977) Effect of polyoxin on fungi VIII. Microscopic observation of bursting of the bulbous germ tubes of polyoxin-treated Alternaria kikuchiana Tanaka in pear leaf extract. Ann Phytopathol Soc Jpn 43: 471–474
Lyr H (1987) Modern selective fungicides. VEB Gustav Fischer, Jena
Lyr H, Werner P (1982) On the mechanism of action of the fungicide chloroneb. Pestic Biochem Physiol 18: 69–76
Meingassner JG, Sleytr U, Petranyi G (1981) Morphological changes induced by naftifine, a new antifungal agent, in Trichophyton mentagrophytes. J Invest Dermatol 77:444–451
Pring RJ, Richmond DV (1976) An ultrastructural study of the effect of oxycarboxin on Uromyces phaseoli infecting leaves of Phaseolus vulgaris. Physiol Plant Pathol 8: 155–162
Richmond DV, Pring RJ (1971) The effect of benomyl on the fine structure of Botrytis fabae. J Gen Microbiol 66: 79–94
Sancholle M, Dargent R, Weete JD, Rushing AE, Miller KS, Montant C (1988) Effects of triazoles on fungi. VI. Ultrastructure of Taphrina deformans. Mycologia 80: 162–175
Smolka S, Ebrahim-Nesbat F, Wolf G (1988) Elektronenmikroskopische Untersuchungen zur Beeinflussung der Wirt-Parasit-Beziehung Gerste-Mehltau durch Triadimenol (Baytan). Z Pflanzenkr Pflanzenschutz 95: 270–284
Steel CC, Baloch RI, Mercer EI, Baldwin BC (1989) The intracellular location and physiological effects of abnormal sterols in fungi grown in the presence of morpholine and functionally related fungicides. Pestic Biochem Physiol 33: 101–111
Stössel P, Lazarovitis G, Ward EWB (1982) Light and electron microscopy of Phytophthora rot in soybeans treated with metalaxyl. Phytopathology 72: 106–111
Trigiano RN, Van Dyke CG, Spurr HW (1984) Effects of metalxyl on Peronospora tabacina infecting tabacco. Phytopathology 74: 1034–1040
Trinci APJ, Ryley JF (1984) Mode of action of antifungal agents. Cambridge University Press, Cambridge
Wolkow PM, Sisler HD, Vigil EL (1983) Effect of inhibitors of melanin biosynthesis on structure and function of appressoria of Colletotrichum lindemuthianum. Physiol Plant Pathol 22: 55–71
Woloshuk, Sisler GD, Vigil EL (1983) Action of the antipenetrant, tricyclazole, on appressoria of Pyricularia oryzae. Physiol Plant Pathol 22: 245–259
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© 1991 Springer-Verlag Berlin Heidelberg
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Hippe, S. (1991). Influence of Fungicides on Fungal Fine Structure. In: Mendgen, K., Lesemann, DE. (eds) Electron Microscopy of Plant Pathogens. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75818-8_24
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DOI: https://doi.org/10.1007/978-3-642-75818-8_24
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