Abstract
Cell surface components are known to play an important role in cell-to-cell interactions such as recognition, communication and adhesion (Nicolson, 1984; Liotta, 1987; Gabius et al, 1987). Such interactions are important during tumorigenesis, tumor progression and metastasis. Cell surface glycoconjugates, particularly, are known to be involved in the complex process of metastasis. The precise biochemical nature of the molecules involved and their relation to tumor progression is not known.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Belloni PN, Tressler RJ and Nicolson GL (1987) Endothelial cell surface glycoprotein associated with preferential adhesion of metastatic murine RAW117 large cell lymphoma to organ-derived microvessel endothelial cells. J. Cell Biochm 11D, 95.
Brunson KW and Nicolson GL (1978) Selection and biologic properties of malignant variants of a murine lymphosarcoma. J NC I 61: 1499–1503.
Gabius HJ, Bandlow G, Schirrmacher V, Nagel GA and Vehmeyer K (1987) Differential expression of endogenous sugar-binding proteins (lectins) in murine tumor model systems with metastatic capacity. Int.J. Cancer 39: 643–648.
Gorielik E, Fogel M, Segal S and Feldman M (1979) Tumor associated antigenic differences between the primary and the descendent metastatic tumor cell populations. J Supra Molecular Struct 12: 385–402.
Joshi SS, Tsaparikos KE, Loh J and Brunson KW (1983) Effects of the antibiotic tunicamycin on RAW117-murine lymphosarcoma cells. Proc. Indiana Acad Sci 92: 321–331.
Joshi SS, Sharp JG and Brunson KW (1987a) Differential growth characteristics of low and high metastatic variant RAW117 murine lymphosarcoma cells. Oncology 44: 180–185.
Joshi SS, Tilden PA, Jackson JD, Sharp JG and Brunson KW (1987b) Cell surface properties associated with malignancy of metastatic large cell lymphoma cells. Cancer Res 47: 3551–3557.
Joshi SS, Sharp JG, Gharpure HM and Brunson KW (1987c) Characterization of metastasis associated antigens on metastatic variant RAW117 lymphosarcoma cell lines. Clin Exp Metastasis 5: 89–104.
Joshi SS, Sharp JG, Gharpure HM and Brunson KW (1987c) Characterization of metastasis associated antigens on metastatic variant RAW117 lymphosarcoma cell lines. Clin Exp Metastasis 5: 89–104.
Joshi SS, Oconnor SJ, Weisenburger DD, Sharp JG and Brunson KW (1987e) Metastatic lymphoma cell specific immunosuppression Proc. Am Asn Cancer Res. 26: 60.
Laemmli Uk (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277: 680–685.
LeGrue SJ, Pellis NR, Riley LB and Kahan BD (1985) Biochemical characterization of 1-butanol-extracted murine tumor-specific transplantation antigens. Cancer Res. 45: 3164–3172.
Liotta LA (1984) Tumor invasion and metastasis: Role of the basement menbrane. Am. J. Pathol. 117: 339–348.
Nicolson GL, Reading CL, Brunson KW (1980) Blood borne tumor metastasis: some properties of selected tumor cell variants of differing malignancies. Crispen G (ed) Tumor Progression, Elsevier/North Holland, Inc., New York, pp 31–38.
McDermott RP, Kienker LJ, Bertovich MJ and Muchmore AV (1981) Inhibition of spontaneous but not antibody dependent cell mediated cytotoxicity by simple sugars: Evidence that endogenous lectins may mediate spontaneous cell mediated cytotoxicity. Immunol. 44: 143–152.
Reading CL, Brunson KW, Torianni M and Nicolson GI (1980) Malignancies of metastatic murine lymphosarcoma cell lines and clones correlate with decreased cell surface display of RNA tumor virus envelope glycoprotein gp70. Proc Natl Acad Sci USA 77: 5943–5947.
Stutman OD, Wisun RE, Lattime EC (1980) Natural cytotoxic cells against solid tumors in mice: blocking of cytotoxicity by D-mannose. Proc. Natl. Acad. Sci. 77: 2895–2898.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Joshi, S.S., Sharp, J.G. (1988). Cell Surface Glycoconjugates Associated with Malignancy/Metastasis of RAW117 Lymphoma Cells. In: Gabius, HJ., Nagel, G.A. (eds) Lectins and Glycoconjugates in Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73662-9_7
Download citation
DOI: https://doi.org/10.1007/978-3-642-73662-9_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73664-3
Online ISBN: 978-3-642-73662-9
eBook Packages: Springer Book Archive