Summary
Metrizamide was injected into the ventricular system of three adults and five children with indwelling ventricular catheters and subcutaneous CSF reservoirs. A first-order rate constant, k, for metrizamide washout from one lateral ventricle was determined with reference to ventricular metrizamide concentration on serial (up to six) postinjection CT scans. Lateral ventricular volume, V v, was estimated after metrizamide injection by a planimetric method and by partial volume analysis, an interactive computerized technique. The rate of lateral ventricular CSF formation, I f, was calculated as k × V v and ranged from 0.0622 to 0.103 ml/min. Precise measurements of lateral ventricular CSF bulk flow depend upon adequate mixing of the injected contrast material with ventricular CSF and accurate measurements of lateral ventricular volume.
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References
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© 1978 Springer-Verlag
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Rottenberg, D.A., Deck, M.D.F., Allen, J.C. (1978). Metrizamide Washout as a Measure of CSF Bulk Flow. In: Wende, S. (eds) Proceedings of the XI. Symposium Neuroradiologicum. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66959-0_66
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DOI: https://doi.org/10.1007/978-3-642-66959-0_66
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-08782-3
Online ISBN: 978-3-642-66959-0
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