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2-Hydroxy-3-Alkyl-1,4-Naphthoquinones

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Mechanism of Action of Antieukaryotic and Antiviral Compounds

Part of the book series: Antibiotics ((1512,volume 5 / 2))

Abstract

At the outbreak of the Second World War, Japanese troops overran the Dutch East Indies, thereby cutting off the Allied Forces from their major source of the antimalarial drug quinine. Faced with entirely inadequate supplies of quinine coupled with the grim prospect of waging tropical warfare in some of the world’s worst malaria-infested regions, the Allied Powers instituted a comprehensive program of research in the chemotherapy of malaria. This program, sponsored and supported by the Committee on Medical Research of the Office of Scientific Research and Development, involved active participation and joint cooperation by academic institutions, pharmaceutical firms, private individuals, and the United States Army, Navy, and Public Health Service.

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Authors
  1. J. G. Olenick
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Editors and Affiliations

  1. Department of the Army, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D.C., 20012, USA

    Fred E. Hahn Ph.D.

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Olenick, J.G. (1979). 2-Hydroxy-3-Alkyl-1,4-Naphthoquinones. In: Hahn, F.E. (eds) Mechanism of Action of Antieukaryotic and Antiviral Compounds. Antibiotics, vol 5 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46407-2_9

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  • DOI: https://doi.org/10.1007/978-3-642-46407-2_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46409-6

  • Online ISBN: 978-3-642-46407-2

  • eBook Packages: Springer Book Archive

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