Editors:
- Discusses therapeutic potential of biased ligands of G protein-coupled receptors
- Describes the molecular mechanisms and therapeutic implications of arrestin-mediated signaling
- Discusses the potential of reengineered signaling proteins for gene therapy
- Includes supplementary material: sn.pub/extras
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 219)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (22 chapters)
-
Front Matter
-
Arrestins and Regulation of G Protein-Coupled Receptors
-
Front Matter
-
-
Arrestin Interactions with Non-receptor Partners and Roles in Cell Signaling
-
Front Matter
-
About this book
This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners.
Editors and Affiliations
-
Professor of Pharmacology, Vanderbilt University Medical Center, Nashville, USA
Vsevolod V. Gurevich
Bibliographic Information
Book Title: Arrestins - Pharmacology and Therapeutic Potential
Editors: Vsevolod V. Gurevich
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/978-3-642-41199-1
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2014
Hardcover ISBN: 978-3-642-41198-4Published: 16 December 2013
Softcover ISBN: 978-3-662-52299-8Published: 23 August 2016
eBook ISBN: 978-3-642-41199-1Published: 29 November 2013
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: VIII, 447
Number of Illustrations: 11 b/w illustrations, 42 illustrations in colour
Topics: Pharmacology/Toxicology, Biochemistry, general, Protein Structure, Gene Therapy, Cell Physiology, Receptors