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Review of Rapid Prototyping Techniques for Tissue Engineering Scaffolds Fabrication

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Characterization and Development of Biosystems and Biomaterials

Part of the book series: Advanced Structured Materials ((STRUCTMAT,volume 29))

Abstract

Tissue engineering scaffold is a 3D construction that acts as a template for tissue regeneration. The scaffold should have some basic requirements including biocompatibility, suitable mechanical properties, appropriate surface chemistry, high porosity and interconnectivity. Although several conventional techniques such as solvent casting and gas forming are utilized in scaffold fabrication, these processes show poor interconnectivity and uncontrollable porosity of the produced scaffolds. However, Rapid Prototyping (RP) techniques which are a group of advanced manufacturing processes can produce custom made objects directly from computer data such as Computer Aided Design (CAD), Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) data. Using RP fabrication techniques, constructions with controllable and complex internal architecture with appropriate mechanical properties can be achieved.The present chapter intends to provide an overview of the current state of the art in the area of tissue engineering scaffolds fabrication, using advanced RP processes. The present work highlights also the existing limitations in addition to future prospects in scaffold fabrication via RP techniques.

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Acknowledgments

The authors would like to thank the cultural affairs and Missions Sector, Ministry of Higher Education—Egypt and Egypt-Japan University of Science and Technology (E-JUST) for supporting this work.

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Authors and Affiliations

  1. Industrial Engineering and Systems Management Department, Egypt–Japan University of Science and Technology (E-JUST), P.O. box 179, New Borg El Arab City, Alexandria 21934, Egypt

    Osama A. M. Abdelaal & Saied M. H. Darwish

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  1. Osama A. M. Abdelaal
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  2. Saied M. H. Darwish
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Correspondence to Osama A. M. Abdelaal .

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Editors and Affiliations

  1. , Faculty Biosciences and, University of Technology Malaysia - UTM, Block A, Building V01, Johor Bahru, 81310, Malaysia

    Andreas Öchsner

  2. , Department of Mechanical Engineering, University of Porto, Rua Dr. Roberto Frias, Porto, 4200-465, Portugal

    Lucas F. M. da Silva

  3. , Lehrstuhl für Technische Mechanik, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, Magdeburg, 39106, Germany

    Holm Altenbach

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Abdelaal, O.A.M., Darwish, S.M.H. (2013). Review of Rapid Prototyping Techniques for Tissue Engineering Scaffolds Fabrication. In: Öchsner, A., da Silva, L., Altenbach, H. (eds) Characterization and Development of Biosystems and Biomaterials. Advanced Structured Materials, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31470-4_3

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