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Handbook of Epidemiology pp 1169–1223Cite as

Clinical Epidemiology

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Abstract

This chapter will begin with providing a brief overview of the history of clinical epidemiology and describe its relation with evidence basedmedicine. Clinical epidemiology differs from classical epidemiology in that clinical epidemiology supports other basic medical sciences such as biochemistry, anatomy and physiology because it facilitates their application in research through formulation of sound clinical research methods and, thus, puts these disciplines into clinical context. Therefore, clinical epidemiology goes beyond clinical trials. We will describe this concept in the following paragraphs (see Sect. 8.1.1 through 8.1.3). The following sections include case scenarios that facilitate the introduction of the key concepts about developing clinical questions, using diagnostic tests, evaluating therapy, appraising systematic reviews, developing guidelines and making clinical decisions.

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Author information

Authors and Affiliations

  1. Departments of Medicine and Social & Preventive Medicine School of Medicine and Biomedical Sciences, University at Buffalo, 270 Farber Hall 3435 Main St, Buffalo, NY, 14214, USA

    Holger J. Schünemann

  2. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

    Holger J. Schünemann

  3. Departments of Medicine and Clinical Epidemiology & Biostatistics, McMaster University Health Sciences Centre, Room 2C12, Hamilton, Ontario, L8N 3Z5, Canada

    Gordon H. Guyatt

Authors
  1. Holger J. Schünemann
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  2. Gordon H. Guyatt
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Editor information

Editors and Affiliations

  1. Division of Epidemiological Methods and Ethiologic Research, Bremen Institute for Prevention Research and Social Medicine (BIPS), Linzer Str. 10, 28359, Bremen, Germany

    Wolfgang Ahrens  & Iris Pigeot  & 

  2. Division of Biometrie and Data Management, Bremen Institute for Prevention Research and Social Medicine (BIPS), Linzer Str. 10, 28359, Bremen, Germany

    Wolfgang Ahrens  & Iris Pigeot  & 

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© 2005 Springer-Verlag Berlin Heidelberg

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Schünemann, H.J., Guyatt, G.H. (2005). Clinical Epidemiology. In: Ahrens, W., Pigeot, I. (eds) Handbook of Epidemiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-26577-1_30

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