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Chronic Headache pp 157–168Cite as

Imaging in CDH

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Abstract

Our understanding of brain abnormalities in headache syndromes has greatly improved with the use of advanced neuroimaging methods. Neuroimaging allows for the noninvasive examination of brain structure and function using modalities such as magnetic resonance imaging (MRI). Measures of brain structure include those that can assess gray matter volume or thickness and white matter microstructure, whereas measures of brain function include those that assess brain activity and connectivity in patients compared to controls. While most studies in the headache literature have examined episodic headache disorders, there has been a recent push toward understanding neuroimaging-based brain abnormalities associated with chronic daily headache (CDH) to gain insight into its underlying pathophysiology. This chapter focuses on studies that have primarily used MRI methods to assess structural and functional brain abnormalities in CDH. These findings are discussed in the context of clinical symptoms and other chronic pain disorders. We conclude with a discussion on future directions for neuroimaging research in CDH.

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Author information

Authors and Affiliations

  1. Neurology and Neurological Sciences, Stanford University, Palo Alto, CA, USA

    Danielle D. DeSouza

  2. Institute of Medical Science, Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Anton Rogachov

Authors
  1. Danielle D. DeSouza
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  2. Anton Rogachov
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Corresponding author

Correspondence to Danielle D. DeSouza .

Editor information

Editors and Affiliations

  1. Department of Headache and Pain Medicine, Icahn School of Medicine at Mt. Sinai, Department of Headache and Pain Medicine, New York, NY, USA

    Mark W. Green

  2. Neurology & Neurological Sciences, Stanford School of Medicine Neurology & Neurological Sciences, Stanford, CA, USA

    Robert Cowan

  3. Department of Neurology, Medical College of Wisconsin, Department of Neurology, Milwaukee, WI, USA

    Frederick G. Freitag

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DeSouza, D.D., Rogachov, A. (2019). Imaging in CDH. In: Green, M., Cowan, R., Freitag, F. (eds) Chronic Headache. Springer, Cham. https://doi.org/10.1007/978-3-319-91491-6_11

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  • DOI: https://doi.org/10.1007/978-3-319-91491-6_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-91490-9

  • Online ISBN: 978-3-319-91491-6

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