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Asymmetric Cell Division in Development, Differentiation and Cancer

  • Book
  • © 2017

Overview

Editors:
  1. Jean-Pierre Tassan

    1. IGDR, UMR 6290, CNRS, Université de Rennes 1, Rennes, France

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  2. Jacek Z. Kubiak

    1. Inst of Genetics & Dev of Rennes IG, CNRS/Unive Rennes 1 UMR 6290, Rennes Cedex, France

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  • Reviews the process of asymmetric cell division extensively
  • Highlights similarities between single-cell and multi-cellular organisms in development
  • Broadens the understanding of tumor development after misregulation in stem cells

Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 61)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-vi
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  2. Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach

    • Ismael Sánchez-Osorio, Carlos A. Hernández-Martínez, Agustino Martínez-Antonio
    Pages 1-21

  3. Spatiotemporal Models of the Asymmetric Division Cycle of Caulobacter crescentus

    • Kartik Subramanian, John J. Tyson
    Pages 23-48

  4. Intrinsic and Extrinsic Determinants Linking Spindle Pole Fate, Spindle Polarity, and Asymmetric Cell Division in the Budding Yeast S. cerevisiae

    • Marco Geymonat, Marisa Segal
    Pages 49-82

  5. Wnt Signaling Polarizes C. elegans Asymmetric Cell Divisions During Development

    • Arielle Koonyee Lam, Bryan T. Phillips
    Pages 83-114

  6. Asymmetric Cell Division in the One-Cell C. elegans Embryo: Multiple Steps to Generate Cell Size Asymmetry

    • Anne Pacquelet
    Pages 115-140

  7. Size Matters: How C. elegans Asymmetric Divisions Regulate Apoptosis

    • Jerome Teuliere, Gian Garriga
    Pages 141-163

  8. The Midbody and its Remnant in Cell Polarization and Asymmetric Cell Division

    • Christian Pohl
    Pages 165-182

  9. Drosophila melanogaster Neuroblasts: A Model for Asymmetric Stem Cell Divisions

    • Emmanuel Gallaud, Tri Pham, Clemens Cabernard
    Pages 183-210

  10. Asymmetric Divisions in Oogenesis

    • Szczepan M. Bilinski, Jacek Z. Kubiak, Malgorzata Kloc
    Pages 211-228

  11. Asymmetric Localization and Distribution of Factors Determining Cell Fate During Early Development of Xenopus laevis

    • Radek Sindelka, Monika Sidova, Pavel Abaffy, Mikael Kubista
    Pages 229-241

  12. Asymmetries in Cell Division, Cell Size, and Furrowing in the Xenopus laevis Embryo

    • Jean-Pierre Tassan, Martin Wühr, Guillaume Hatte, Jacek Kubiak
    Pages 243-260

  13. Asymmetric and Unequal Cell Divisions in Ascidian Embryos

    • Takefumi Negishi, Hiroki Nishida
    Pages 261-284

  14. Asymmetries and Symmetries in the Mouse Oocyte and Zygote

    • Agathe Chaigne, Marie-Emilie Terret, Marie-Hélène Verlhac
    Pages 285-299

  15. Symmetry Does not Come for Free: Cellular Mechanisms to Achieve a Symmetric Cell Division

    • Damian Dudka, Patrick Meraldi
    Pages 301-321

  16. A Comparative Perspective on Wnt/β-Catenin Signalling in Cell Fate Determination

    • Clare L. Garcin, Shukry J. Habib
    Pages 323-350

  17. Extracellular Regulation of the Mitotic Spindle and Fate Determinants Driving Asymmetric Cell Division

    • Prestina Smith, Mark Azzam, Lindsay Hinck
    Pages 351-373

  18. Regulation of Asymmetric Cell Division in Mammalian Neural Stem and Cancer Precursor Cells

    • Mathieu Daynac, Claudia K. Petritsch
    Pages 375-399

  19. Molecular Programs Underlying Asymmetric Stem Cell Division and Their Disruption in Malignancy

    • Subhas Mukherjee, Daniel J. Brat
    Pages 401-421
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Keywords

About this book

This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.

To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.



Editors and Affiliations

  • IGDR, UMR 6290, CNRS, Université de Rennes 1, Rennes, France

    Jean-Pierre Tassan

  • Inst of Genetics & Dev of Rennes IG, CNRS/Unive Rennes 1 UMR 6290, Rennes Cedex, France

    Jacek Z. Kubiak

Bibliographic Information

  • Book Title: Asymmetric Cell Division in Development, Differentiation and Cancer

  • Editors: Jean-Pierre Tassan, Jacek Z. Kubiak

  • Series Title: Results and Problems in Cell Differentiation

  • DOI: https://doi.org/10.1007/978-3-319-53150-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-53149-6Published: 25 April 2017

  • Softcover ISBN: 978-3-319-85077-1Published: 21 July 2018

  • eBook ISBN: 978-3-319-53150-2Published: 12 April 2017

  • Series ISSN: 0080-1844

  • Series E-ISSN: 1861-0412

  • Edition Number: 1

  • Number of Pages: VI, 421

  • Number of Illustrations: 15 b/w illustrations, 81 illustrations in colour

  • Topics: Cell Cycle Analysis, Embryology, Stem Cells, Cancer Research

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