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Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources

  • Book
  • © 2017

Overview

Editors:
  1. Guillermo Gosset

    1. Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Mexico

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  • Focuses on the specific topic of microbial strain generation and improvement for the utilization of renewable raw materials

  • Written by respected experts in each field

  • Provides state-of-the-art information

  • Includes supplementary material: sn.pub/extras

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-vii
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  2. Recent Advances in Genetic Engineering of Thermophilic Ethanol Producing Bacteria

    • Sean Michael Scully, Johann Orlygsson
    Pages 1-29

  3. Systems Metabolic Engineering of Saccharomyces cerevisiae for Production of Biochemicals from Biomass

    • Luis Caspeta, Tania Castillo
    Pages 31-65

  4. Zymomonas mobilis for the Conversion of Lignocellulosic Biomass to Fuels and Chemicals

    • Manoj Agrawal, Kori L. Dunn, Christopher V. Rao
    Pages 67-92

  5. Glycerol as Carbon Source for Production of Added-Value Compounds

    • Georg A. Sprenger
    Pages 93-123

  6. Metabolic Engineering of Escherichia coli for Lactic Acid Production from Renewable Resources

    • Alfredo Martinez, María E. Rodríguez-Alegría, Maria Conceição Fernandes, Guillermo Gosset, Alejandra Vargas-Tah
    Pages 125-145

  7. Engineering Bacterial Sugar Catabolism and Tolerance Toward Lignocellulose Conversion

    • Andrew D. Flores, Gavin L. Kurgan, Xuan Wang
    Pages 147-180

  8. Evolutionary Engineering of Microorganisms to Overcome Toxicity During Lignocellulose Hydrolysates Utilization

    • Gustavo M. Lastiri-Pancardo, José Utrilla
    Pages 181-200
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Keywords

About this book

This book reviews state of the art regarding strategies for generating and improving microbial strains designed for utilizing renewable raw materials. It discusses methods for genetically engineering of thermophilic bacteria, Saccharomyces cerevisiae, Escherichia coli and Zymomonas mobilis, as well as approaches for obtaining useful products from these renewable raw materials based on biotechnological processes using microbes to chemically transform them. However, the efficient transformation of lignocellulosic biomass or glycerol to useful products represents a major challenge: Biomass has to be treated physically and chemically to release a mixture of sugars that potentially can be employed by the microbial production strains. These hydrolytic treatments result in diverse toxic compounds being generated and released, that negatively impact strain performance. Furthermore, most of the commonly used industrial microbes do not have the natural capacity to efficiently utilize and transform the generated sugar mixtures or glycerol.

The microbial species reviewed in this book possess particular advantages as production strains and are currently employed for the synthesis of numerous biofuels and chemicals. The book reviews the general and strain-specific genetic engineering strategies for the improvement of sugar mixtures and glycerol catabolism. The issue of lignocellulosic hydrolysate toxicity is addressed in several chapters, where genetic engineering and adaptive laboratory evolution strategies are reviewed and discussed.

The objective of this book is to provide the current knowledge regarding strategies for the generation and improvement of microbial strains designed for the transformation of renewable raw materials into useful products. This book aims to become a reference for researchers and students working in this field.

Editors and Affiliations

  • Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Mexico

    Guillermo Gosset

About the editor

Guillermo Gosset obtained his Ph.D. degree in Biotechnology from the Universidad Nacional Autónoma de México (UNAM) in 1993. Since 1988 he has been a research scientist at the Biotechnology Institute/UNAM. His main research interests are related to metabolic pathway engineering and microbial physiology. Gosset’s work has appeared in more than 105 publications and eight patents. Several of these publications are utilized as examples in textbooks in the field of metabolic engineering. His industrial experience includes two years as a visiting scientist at Genencor International (Palo Alto, U.S.A.) and one year in Metabolic Explorer (Clermont-Ferrand, France). He has been a Senior Editor on the editorial board of the Journal of Molecular Microbiology and Biotechnology since 2006 and Associate Editor of Microbial Cell Factories since 2014.

Bibliographic Information

  • Book Title: Engineering of Microorganisms for the Production of Chemicals and Biofuels from Renewable Resources

  • Editors: Guillermo Gosset

  • DOI: https://doi.org/10.1007/978-3-319-51729-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • License: CC BY

  • Hardcover ISBN: 978-3-319-51728-5Published: 09 February 2017

  • Softcover ISBN: 978-3-319-84728-3Published: 28 July 2018

  • eBook ISBN: 978-3-319-51729-2Published: 26 January 2017

  • Edition Number: 1

  • Number of Pages: VII, 200

  • Number of Illustrations: 3 b/w illustrations, 15 illustrations in colour

  • Topics: Biomedical Engineering/Biotechnology, Biotechnology

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