Comparative Medicine

1. Front Matter

   Pages i-xix

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2. Failure in Cardiac Action: Comparing Humans, Dogs, Cats, and Horses

   • Claudia Stöllberger, Mateo Markovic

   Pages 1-12

3. Epilepsy in Humans and Animals: From Patients to Disease Models

   • Josef Finsterer, Akos Pakozdy, Monika Bradl

   Pages 13-25

4. Chronic Kidney Failure Affects Humans and Other Mammalians

   • Renate Kain, Maximilian Pagitz

   Pages 27-46

5. Inflammatory Bowel Disease in Humans, Pets, and Horses

   • Franziska Roth-Walter, Sonja Berger, Nicole Luckschander-Zeller

   Pages 47-69

6. Out of Breath: Asthma in Humans and Their Animals

   • Karin Hufnagl, Reinhard Hirt, Bruno Robibaro

   Pages 71-85

7. Comparing Two Major Bone Pathologies in Humans and Companion Animals: Osteoporosis and Hyperparathyroidism

   • Wolfgang Sipos, Ursula Föger-Samwald, Peter Pietschmann

   Pages 87-96

8. Life Out of Balance: Stress-Related Disorders in Animals and Humans

   • Lisa Maria Glenk, Oswald David Kothgassner

   Pages 97-107

9. Allergies, with Focus on Food Allergies, in Humans and Their Animals

   • Isabella Pali-Schöll, Ina Herrmann, Erika Jensen-Jarolim, Christine Iben

   Pages 109-129

10. Allergic and Atopic Eczema in Humans and Their Animals

    • Erika Jensen-Jarolim, Ina Herrmann, Lucia Panakova, Jozef Janda

    Pages 131-150

11. Prophylactic Vaccination Against Papillomavirus-Induced Tumour Disease

    • Sabine Brandt, Edmund Hainisch

    Pages 151-165

12. Tick Bites and Borrelia Infection: A Problem for Mammalian Species

    • Gerold Stanek

    Pages 167-175

13. Parasitic Infections in Humans and Animals

    • Julia Walochnik, Herbert Auer, Anja Joachim

    Pages 177-189

14. Comparing Human Breast Cancer with Canine Mammary Cancer

    • Emir Hadzijusufovic, Michael Willmann

    Pages 191-207

15. Regulatory Animal Testing for the Development of Medicines

    • Günter Waxenecker, Regina Binder

    Pages 209-218

16. One Health: Many Patients? A Short Theory on What Makes an Animal a Patient

    • Herwig Grimm, Martin Huth

    Pages 219-230

This book highlights the most significant diseases for humans and their dogs, cats and horses. The examples discussed, which include allergies, osteoporosis, cancer and many more, illustrate that humans and their companion animals may in fact develop similar diseases.

The reader - whether expert or interested lay - can thus directly compare between human and animal patients. The animal patient thereby represents a natural disease model, which besides the experimental models, is urgently needed to improve the therapeutic options for both humans and animals.

• animal law in medicinal research
• diseases of domesticated animals
• experimental medicine
• pathophysiology of animal models
• animal model

“Covering a subset of diseases that occur in humans and animals, this book compares disease presentation, diagnosis, and therapy focusing on dogs, cats, horses, and humans. … The purpose is to provide a link between clinical and veterinary disciplines to expand how we look at different diseases. … This book would be most useful for medical or veterinary students, residents, practitioners, and research faculty. … On the whole, the goal of this book is achieved.” (Sarah Freemantle, Doody's Book Reviews, May, 2017)

• The interuniversity Messerli Research Institute, Vienna, Austria

  Erika Jensen-Jarolim

Prof. Erika Jensen-Jarolim is head of the Dept. of Pathophysiology of the Medical University Vienna. She holds an MD and is specialized in pathophysiology and immunology. Based on her active interest in comparative oncology she since 2008 is councilor of the University of Veterinary Medicine Vienna. Her research is dedicated to comparative strategies in order to simultaneously speed up diagnostic and therapeutic developments for human and animal patients, especially in the allergy and oncology fields.

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