Psychoneuroimmunology

1. Front Matter

   Pages i-xiii

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2. Psychoneuroimmunology and Systems Biology Mechanisms

   1. Front Matter

      Pages 1-1

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   2. From Psychoneuroimmunology to Personalized, Systems, and Dynamical Medicine

      • Qing Yan

      Pages 3-9

   3. Stress and Inflammation: Translational Implications in Mind–Body Medicine

      • Qing Yan

      Pages 11-17

   4. Biological Rhythms and the HPA Axis in Psychoneuroimmunology

      • Qing Yan

      Pages 19-26

   5. The Inflammatory Networks and Dynamical Patterns in Psychoneuroimmunology

      • Qing Yan

      Pages 27-35

3. Psychoneuroimmunology, Diseases, and Mind-Body Medicine

   1. Front Matter

      Pages 37-37

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   2. Sleep, Psychoneuroimmunology, and Mind–Body Medicine

      • Qing Yan

      Pages 39-42

   3. Psychoneuroimmunology of Depression

      • Qing Yan

      Pages 43-52

   4. Psychoneuroimmunology of Schizophrenia

      • Qing Yan

      Pages 53-63

   5. Obesity, Stress, Inflammation, and Psychoneuroimmunology

      • Qing Yan

      Pages 65-74

   6. Psychoneuroimmunology of Aging

      • Qing Yan

      Pages 75-85

   7. Psychoneuroimmunology of Cardiovascular Diseases

      • Qing Yan

      Pages 87-95

   8. Psychoneuroimmunology and Cancer

      • Qing Yan

      Pages 97-108

   9. Psychoneuroimmunology of Skin Diseases

      • Qing Yan

      Pages 109-120

   10. The Translation of Psychoneuroimmunology into Mind–Body Medicine

       • Qing Yan

       Pages 121-129

4. Back Matter

   Pages 131-136

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This book provides a comprehensive overview of the cutting-edge discoveries and the systems approaches related to the multi-disciplinary field of psychoneuroimmunology (PNI), which may provide the scientific basis for mind-body relationships, and aid in the development of personalized medicine. Specifically, the book focuses on the systems biology studies of complex mechanisms, such as stress and inflammation. There is strong evidence supporting the close relationship between stress, inflammation, and disorders including obesity, cardiovascular disease, diabetes, skin diseases, and sleep disorders. As inflammation is a critical connection among different diseases, further elucidating this connection may contribute to the findings of systemic therapeutic targets. Translational medicine is also addressed, by applying PNI approaches in clinical practice. A major challenge in current bioscience is the translation of basic scientific discoveries into better clinical outcomes. With the understanding of the translational implications of PNI, integrative interventions can be applied to modulate stress responses and to promote healthier behaviors. As an important feature of this book, a broad overview of the PNI-associated integrative interventions is provided. These interventions include nutritional supplements, meditation, and other mind-body strategies. From basic concepts to systems methodologies, from theoretical sources to clinical applications, Psychoneuroimmunology contributes to the understanding and development of PNI toward the establishment of personalized and mind-body medicine.

• brain
• inflammation
• personalized medicine
• psychoneuroimmunology
• systems biology

• PharmTao, Santa Clara, USA

  Qing Yan

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