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Oligodendroglioma, Cytological Findings

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  • First Online:
Cytopathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 145 Accesses

Synonyms

Glioma

Definition

Neoplasia composed of cells resembling oligodendroglia.

Clinical Features

  • Incidence

    The incidence has been estimated to be 0,27–0,35 per 100,000 persons and correspond to 5–6% of gliomas.

  • Age

    The oligodendroglioma has a peak of incidence between 40 and 45 years.

  • Sex

    Men show slightly greater incidence than women at a ratio of 1.1:1.

  • Site

    The oligodendrogliomas occur predominantly in the cortex and white matter of the cerebral hemisphere and the frontal lobe involved in 50–65% of cases.

  • Treatment

    The treatment of patients with oligodendroglioma involves surgery, radiotherapy, and chemotherapy.

Outcome

Patients with oligodendrogliomas have median survival from 4.4 to 9.8 years with survival rates of 38–75% after 5 years and 19–59% after 10 years.

Macroscopy

Oligodendroglioma usually presents as diffuse neoplasm with grayish-pink color, gelatinous consistency with poorly defined margins, and areas of calcification.

Microscopy

In cytological smears...

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References and Further Reading

  • Bigner, S. H., & Carter, A. L. (2008). Central nervous system. In M. Bibbo & D. C. Wilbur (Eds.), Comprehensive cytopathology. Philadelphia: Saunders Elsevier.

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  • Giangaspero, F., Eberharth, C. G., Pietsch, T., Wiestler, O. D., & Ellinson, D. W. (2007). Medulloblastoma. In D. N. Louis & H. Ohgaki (Eds.), Who classification of tumours of the central nervous system. Lyon: IARC.

    Google Scholar 

  • Moss, T. H., Nicoll, J. A. R., & Ironside, J. W. (1997). Intra-operative diagnosis of central nervous tumours. London: Arnould.

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  • Torres, L. F. B., & Collaco, L. M. (1992). Smear technique for the intraoperative examination of nervous system lesions. Acta Cytologica, 37, 34–39.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Evangelical Faculty of Parana, Federal University of Parana, 324 – Bela Vista, Curitiba, PR, CEP 01333-903, Brazil

    Luiz M. Collaço

  2. Evangelical Faculty of Parana, Catholic University of Parana, Rua Padre Anchieta 2770, Curitiba-PR, CEP 80.730, Brazil

    Ana Cristina Lira Sobral

Authors
  1. Luiz M. Collaço
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  2. Ana Cristina Lira Sobral
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Corresponding authors

Correspondence to Luiz M. Collaço or Ana Cristina Lira Sobral .

Editor information

Editors and Affiliations

  1. Laboratoire national de santé, Luxembourg City, Luxembourg

    Fernando Schmitt

  2. Medical Faculty of Porto University and IPATIMUP, Porto, Portugal

    Fernando Schmitt

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© 2017 Springer-Verlag Berlin Heidelberg

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Collaço, L.M., Sobral, A.C.L. (2017). Oligodendroglioma, Cytological Findings. In: Schmitt, F. (eds) Cytopathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-33286-4_846

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  • DOI: https://doi.org/10.1007/978-3-319-33286-4_846

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-33285-7

  • Online ISBN: 978-3-319-33286-4

  • eBook Packages: MedicineReference Module Medicine

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