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Current Understanding and Treatment of Gliomas pp 159–170Cite as

Glioblastoma in the Elderly

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Part of the book series: Cancer Treatment and Research ((CTAR,volume 163))

Abstract

There is no generally agreed upon standard of care treatment for elderly patients (age ≥70 years) with glioblastoma (GBM). Treatment options range from supportive care only, radiation therapy (RT) only (most often given in a shortened hypofractionated schedule), temozolomide (TMZ) chemotherapy only, and the combination RT + TMZ, followed by post-RT TMZ as is the current standard of care for younger good performance patients with newly diagnosed GBM.

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Authors and Affiliations

  1. Department of Neurology and Neurological Surgery, University of Washington/Fred Hutchison Cancer Research Center, Seattle Cancer Care Alliance, 825 Eastlake Ave East MS G4940, Box 19023, Seattle, WA, 98109, USA

    Marc C. Chamberlain

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  1. Marc C. Chamberlain
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Correspondence to Marc C. Chamberlain .

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Editors and Affiliations

  1. Department of Neurology, Northwestern University, Chicago, Illinois, USA

    Jeffrey Raizer

  2. Department of Neurosurgery, Northwestern University, Chicago, Illinois, USA

    Andrew Parsa

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Chamberlain, M.C. (2015). Glioblastoma in the Elderly. In: Raizer, J., Parsa, A. (eds) Current Understanding and Treatment of Gliomas. Cancer Treatment and Research, vol 163. Springer, Cham. https://doi.org/10.1007/978-3-319-12048-5_10

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  • DOI: https://doi.org/10.1007/978-3-319-12048-5_10

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