Abstract
The application of cardiovascular CT imaging toward the detection, characterization, and prognostication of coronary artery disease (CAD) is one of the most rapidly evolving and exciting aspects of cardiovascular medicine. Coronary computed tomographic angiography (CCTA) has revolutionized the diagnosis and management of coronary artery disease by providing new methods for noninvasive imaging of coronary arteries. Coronary arterial calcification of plaques, plaque progression, stenosis characterization, plaque analysis, and appropriate use criteria will be presented below.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Margolis JR, et al. The diagnostic and prognostic significance of coronary artery calcification. A report of 800 cases. Radiology. 1980;137(3):609–16.
Kondos GT, et al. Electron-beam tomography coronary artery calcium and cardiac events: a 37-month follow-up of 5635 initially asymptomatic low- to intermediate-risk adults. Circulation. 2003;107(20):2571–6.
O’Rourke RA, et al. American College of Cardiology/American Heart Association Expert Consensus document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease. Circulation. 2000;102(1):126–40.
Budoff MJ, et al. Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients. J Am Coll Cardiol. 2007;49(18):1860–70.
Detrano R, et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med. 2008;358(13):1336–45.
Polonsky TS, et al. Coronary artery calcium score and risk classification for coronary heart disease prediction. JAMA. 2010;303(16):1610–6.
Arad Y, et al. Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial. J Am Coll Cardiol. 2005;46(1):166–72.
Kroft LJ, de Roos A, Geleijns J. Artifacts in ECG-synchronized MDCT coronary angiography. AJR Am J Roentgenol. 2007;189(3):581–91.
Budoff MJ, et al. Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. J Am Coll Cardiol. 2008;52(21):1724–32.
Voros S, et al. Coronary atherosclerosis imaging by coronary CT angiography: current status, correlation with intravascular interrogation and meta-analysis. JACC Cardiovasc Imaging. 2011;4(5):537–48.
Ehara S, et al. Spotty calcification typifies the culprit plaque in patients with acute myocardial infarction: an intravascular ultrasound study. Circulation. 2004;110(22):3424–9.
Virmani R, et al. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 2000;20(5):1262–75.
Glagov S, et al. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med. 1987;316(22):1371–5.
Motoyama S, et al. Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome. J Am Coll Cardiol. 2009;54(1):49–57.
Raff GL, et al. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol. 2005;46(3):552–7.
Raff GL, et al. SCCT guidelines for the interpretation and reporting of coronary computed tomographic angiography. J Cardiovasc Comput Tomogr. 2009;3(2):122–36.
Rispler S, et al. Integrated single-photon emission computed tomography and computed tomography coronary angiography for the assessment of hemodynamically significant coronary artery lesions. J Am Coll Cardiol. 2007;49(10):1059–67.
George RT, et al. Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320-MDCT: the CT angiography and perfusion methods of the CORE320 multicenter multinational diagnostic study. AJR Am J Roentgenol. 2011;197(4):829–37.
Achenbach S, et al. Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography: a segment-based comparison with intravascular ultrasound. Circulation. 2004;109(1):14–7.
Schoenhagen P, et al. Non-invasive assessment of plaque morphology and remodeling in mildly stenotic coronary segments: comparison of 16-slice computed tomography and intravascular ultrasound. Coron Artery Dis. 2003;14(6):459–62.
Hoffmann U, et al. Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography. J Am Coll Cardiol. 2006;47(8):1655–62.
Schmermund A, Mohlenkamp S, Schlosser T, Raimund E. Coronary angiography after revascularization. In: Budoff MJ, Shinbane JS, editors. Cardiac CT imaging: diagnosis of cardiovascular disease. London: Springer; 2006. p. 135–45.
Jen-Sho Chen J, White C. CT angiography for coronary artery bypass graft surgery. Appl Radiol. 2008;37:10–8.
Martuscelli E. Coronary artery bypass grafts. In: Dewey M, editor. Cardiac CT. Berlin: Springer; 2011. p. 171–8.
Anders K. Coronary artery stents. In: Dewey M, editor. Cardiac CT. Berlin: Springer; 2011. p. 179–90.
Mahnken A. CT imaging of coronary stents: past, present, and future. ISRN Cardiol. 2012;2012:1–12.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Musani, M.H., Vainrib, A., Gupta, R., Poon, M. (2015). Coronary Artery Disease Evaluation Using Cardiac CTA. In: Clinical Pearls in Diagnostic Cardiac Computed Tomographic Angiography. Springer, Cham. https://doi.org/10.1007/978-3-319-08168-7_4
Download citation
DOI: https://doi.org/10.1007/978-3-319-08168-7_4
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-08167-0
Online ISBN: 978-3-319-08168-7
eBook Packages: MedicineMedicine (R0)