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Mammalian Transient Receptor Potential (TRP) Cation Channels

Volume II

  • Book
  • © 2014

Overview

Editors:
  1. Bernd Nilius

    1. Laboratory Ion Channel Research, Campus Gasthuisberg, KU Leuven Department, Cell Mol Medicin, Leuven, Belgium

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  2. Veit Flockerzi

    1. Pharmakologie und Toxikologie, Universität des Saarlandes, Institut für Experimentelle u. Klinische, Homburg, Germany

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  • This book provides excellent up-to-date information on mammalian TRP cation channels, a rapidly moving field
  • Broadens understanding of TRP as special cell sensors
  • Current findings in this field are critically discussed by the Editors

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 223)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xi
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  2. TRPs as Special Cell Sensors

    1. TRP Channels and Thermosensation

      • Thomas Voets
      Pages 729-741

    2. TRPs in Mechanosensing and Volume Regulation

      • Tim D. Plant
      Pages 743-766

    3. TRPs as Chemosensors (ROS, RNS, RCS, Gasotransmitters)

      • Shunichi Shimizu, Nobuaki Takahashi, Yasuo Mori
      Pages 767-794

    4. Photosensitive TRPs

      • Roger C. Hardie
      Pages 795-826

    5. TRPs in Taste and Chemesthesis

      • Stephen D. Roper
      Pages 827-871

    6. TRPs and Pain

      • Jane E. Sexton, Jeffrey Vernon, John N. Wood
      Pages 873-897

    7. TRPs in Hearing

      • Damiano Zanini, Martin C. Göpfert
      Pages 899-916

    8. TRPs in Olfaction

      • Frank Zufall
      Pages 917-933

  3. General Topics

    1. Evolutionarily Conserved, Multitasking TRP Channels: Lessons from Worms and Flies

      • Kartik Venkatachalam, Junjie Luo, Craig Montell
      Pages 937-962

    2. Structural Biology of TRP Channels

      • Ute A. Hellmich, Rachelle Gaudet
      Pages 963-990

    3. High-Resolution Views of TRPV1 and Their Implications for the TRP Channel Superfamily

      • Ute A. Hellmich, Rachelle Gaudet
      Pages 991-1004

    4. Physiological Functions and Regulation of TRPC Channels

      • Hwei Ling Ong, Lorena B. de Souza, Kwong Tai Cheng, Indu S. Ambudkar
      Pages 1005-1034

    5. The TRPCs–STIM1–Orai Interaction

      • Seok Choi, Jozsef Maleth, Archana Jha, Kyu Pil Lee, Min Seuk Kim, Insuk So et al.
      Pages 1035-1054

    6. The TRPC Family of TRP Channels: Roles Inferred (Mostly) from Knockout Mice and Relationship to ORAI Proteins

      • Yanhong Liao, Joel Abramowitz, Lutz Birnbaumer
      Pages 1055-1075

    7. TRPs: Modulation by Drug-Like Compounds

      • Michael Schaefer
      Pages 1077-1106

    8. TRP Channels in Reproductive (Neuro)Endocrinology

      • Trese Leinders-Zufall, Ulrich Boehm
      Pages 1107-1118

    9. Modulation of TRP Ion Channels by Venomous Toxins

      • Jan Siemens, Christina Hanack
      Pages 1119-1142

    10. Phosphoinositide Regulation of TRP Channels

      • Tibor Rohacs
      Pages 1143-1176

    11. TRP Modulation by Natural Compounds

      • Flavia Carla Meotti, Edinéia Lemos de Andrade, João B. Calixto
      Pages 1177-1238
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Keywords

About this book

​In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

Editors and Affiliations

  • Laboratory Ion Channel Research, Campus Gasthuisberg, KU Leuven Department, Cell Mol Medicin, Leuven, Belgium

    Bernd Nilius

  • Pharmakologie und Toxikologie, Universität des Saarlandes, Institut für Experimentelle u. Klinische, Homburg, Germany

    Veit Flockerzi

Bibliographic Information

  • Book Title: Mammalian Transient Receptor Potential (TRP) Cation Channels

  • Book Subtitle: Volume II

  • Editors: Bernd Nilius, Veit Flockerzi

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-319-05161-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2014

  • Hardcover ISBN: 978-3-319-05160-4Published: 10 July 2014

  • Softcover ISBN: 978-3-319-35878-9Published: 23 August 2016

  • eBook ISBN: 978-3-319-05161-1Published: 24 June 2014

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XI, 565

  • Number of Illustrations: 19 b/w illustrations, 50 illustrations in colour

  • Topics: Pharmacology/Toxicology, Human Physiology, Molecular Medicine

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