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Personalized Anesthesia for GI Tract and Hepatobiliary System

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Personalized Medicine in Anesthesia, Pain and Perioperative Medicine

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Abstract

Routinely and traditionally anesthesia practice and dosing of drugs is based on patients’ responses which usually resulted in over or under dosing. These fluctuations in responsiveness complicate the ability to induce a safe anesthesia. Hepatobiliary tract as the main place for drug metabolism has an important role in proteomics and metabolomics and more future studies are required to identify the genetic contribution to anesthetics and prevent complication during anesthesia and post-operative period. Although our gut as the main source of our microbiome has the essential role in pathology of different disease (organ-organ interaction like gut-brain /gut-lung axis) so considering microbiomics is an essential part in providing anesthesia practice especially in GI tract surgeries. Traditional anesthesia cannot be totally ruled out, it is evident that personalized anesthesia is shaping the future of this practice and stands a promising chance of overtaking conventional anesthesia in the future. Personalized anesthesia provides a kinetic energy to ideal change in the health care system and improve in the quality of care. In this chapter we discuss the different aspects of personalized anesthesia (metabolomics/ proteomics/ microbiomics) regarding GI tract and hepatobiliary system.

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Authors and Affiliations

  1. Department of Anesthesiology, School of Medicine, Shohada Medical Research & Training Hospital, Tabriz University of Medical Sciences, Tabriz, Iran

    Ata Mahmoodpoor

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  1. Ata Mahmoodpoor
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Editors and Affiliations

  1. Cardiac Anesthesiology Department, Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Ali Dabbagh

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Mahmoodpoor, A. (2021). Personalized Anesthesia for GI Tract and Hepatobiliary System. In: Dabbagh, A. (eds) Personalized Medicine in Anesthesia, Pain and Perioperative Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-53525-4_9

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  • DOI: https://doi.org/10.1007/978-3-030-53525-4_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-53524-7

  • Online ISBN: 978-3-030-53525-4

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