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The Genetics of Mitral Valve Prolapse

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Clinical Cardiogenetics

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Abstract

Mitral valve prolapse (MVP) is one of the most common forms of valvular heart disease. The clinical presentation can be very diverse, ranging from an incidental finding within asymptomatic patients to dramatic cases with severe mitral regurgitation, heart failure, bacterial endocarditis, or even sudden cardiac death. Mitral valve prolapse appears to be one of the most common Mendelian cardiovascular abnormalities in humans. This chapter briefly discusses the epidemiologic aspects of mitral valve prolapse, its pathophysiology, and the current status of genetic knowledge of this intriguing valvular disorder.

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Authors and Affiliations

  1. Department of Cardiology, Antonius Hospital Sneek, 20000, BA 8600, Sneek, The Netherlands

    Paul L. van Haelst

Authors
  1. Paul L. van Haelst
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  2. Toon Oomen
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  3. J. Peter van Tintelen
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Corresponding author

Correspondence to Paul L. van Haelst .

Editor information

Editors and Affiliations

  1. University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, 3508 GA, Netherlands

    H.F. Baars

  2. University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, 3508 GA, Netherlands

    P.A.F.M. Doevendans

  3. University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, 3508 GA, Netherlands

    J.J. van der Smagt

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© 2011 Springer-Verlag London Limited

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van Haelst, P.L., Oomen, T., van Tintelen, J.P. (2011). The Genetics of Mitral Valve Prolapse. In: Baars, H., Doevendans, P., van der Smagt, J. (eds) Clinical Cardiogenetics. Springer, London. https://doi.org/10.1007/978-1-84996-471-5_15

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  • DOI: https://doi.org/10.1007/978-1-84996-471-5_15

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84996-470-8

  • Online ISBN: 978-1-84996-471-5

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