Abstract
One new tocopherol analogue, methoxytocopherol (1), and two known analogues, α-tocopherol (2) and γ-tocopherol (3), were isolated from the peels of Citrus unshiu Marcovich. The chemical structures of compounds 1–3 were determined by interpretation of spectroscopic data. All isolated compounds were evaluated for radical-scavenging capacity using 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt, 1,1-diphenyl-2-picrylhydrazyl, and oxygen radical absorbance capacity assays.
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References
Floegel A, Kim DO, Chung SJ, Song WO, Fernandez ML, Bruno RS et al. (2010) Development and validation of an algorithm to establish a total antioxidant capacity database of the US diet. Int J Food SciNutr 61, 600–623.
Gadow AV, Joubert E, and Hansmann CF (1997) Comparison of the antioxidant activity of aspalathin with that of other plant phenols of Rooibos tea (Aspalathus linearis) α-tocopherol, BHT, and BHA. J Agric Food Chem 45, 632–638.
Han NM, May CY, Ngan MA, Hock CC, and Hashim MA (2004) Isolation of palm tocols using supercritical fluid chromatography. J Chromatogr Sci 42, 536–539.
Hong SC, Byun SH, and Kim SS (1987) In Colored illustrations of trees and shrubs in Korea. KyeMyeong Sa, Korea.
Huang D, Ou B, Hampsch-Woodill M, Flanagan JA, and Prior RL (2002) High-throughput assay of oxygen radical absorbance capacity (ORAC) using a multichannel liquid handling system coupled with a microplate fluorescence reader in 96-well format. J Arg Food Chem 50, 4437–4444.
Jung JK, Son KH, Kim YS, and Park YK (2011) Effect of Citri Pericarpium ethanol extract on collagen-induced arthritis in mice. Kor J Herbology 26, 1–6.
Kato M, Ikoma Y, Matsumoto H, Sugiura M, Hyodo H, and Yano M (2004) Accumulation of carotenoids and expression of carotenoid biosynthetic genes during maturation in Citrus fruits. Plant Physiol 134, 824–837.
Kim DO, Lee KW, LEE HJ, and LEE CY (2002) Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. J Agr Food Chem 50, 3713–3717.
Lee BH, Cho TS, and Lee WC (1974) Pharmacological actions of extracts of Citrus unshiu pericarpium on cardiovascular system. Korean J of Pharmacology 10, 103–109.
Liu JK, Hu L, Dong ZJ, and Hu Q (2004) DPPH radical scavenging activity of ten natural p-terphenyl derivatives obtained from three edible mushrooms indigenous to China. Chem Biodiversity 1, 601–605.
Montforte MT, Trovato A, Kirjavainen S, Forestieri AM, Galati EM, and Lo Cutro RB (1995) Biological effects of hesperidin a citrus flavonoid hypolipidemic activity on experimental hypercholesterolemia in rat. Il Farmaco 50, 595–599.
Park YS, Kim SJ, and Chang HI (2008) Isolation of anthocyanin from black rice (Heungjinjubyeo) and screening of its antioxidant activities. Kor J Microbiol Biotechnol 36, 55–60.
Sawabe A, Morita A, Kiso T, Kishine H, Ohtsubo Y, Minematsu T et al. (1999) Isolation and characterization of new limonoid glycosides from Citrus unshiu peels. Carbohydr Res 315, 142–147.
Wang Y, Yang M, Lee SG, Davis CG, Kenny A, Koo SI et al. (2012) Plasma total antioxidant capacity is associated with dietary intake and plasma level of antioxidant in postmenopausal women. J Nutr Biochem 23, 1725–1731.
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Seo, KH., Lee, DY., Nam, TG. et al. New tocopherol analogue with radical-scavenging activity from the peels of Citrus unshiu Marcovich. J Korean Soc Appl Biol Chem 56, 747–750 (2013). https://doi.org/10.1007/s13765-013-3230-6
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DOI: https://doi.org/10.1007/s13765-013-3230-6