The Neurocritical Care Research Network: NCRN

Abstract

Neurocritical care diseases carry a high morbidity and mortality. Therapeutic and technological advances in neurocritical care have greatly improved the outcome of a variety of life-threatening disorders including traumatic brain injury, acute ischemic stroke, intracerebral and subarachnoid hemorrhage, and anoxic injury following cardiac arrest. These advances have stemmed from a better understanding of the physiology of neurocritical care illnesses, improved neuromonitoring techniques, and the introduction of more efficacious treatments. Despite all the advances in neuromonitoring, diagnostic imaging, and emerging treatments, much research needs to be undertaken in neurocritical care. Many of the clinical trials carried out in the general critical care population have excluded neurocritical care patients. For instance, the landmark ARDSNET trial that demonstrated the beneficial effects of low tidal volume ventilation in patients with ARDS cannot be directly applied to neurocritical care patients who frequently may experience this pulmonary complication. There is a need for a more cohesive and integrated research system or network to establish a track record for high-quality, investigator-initiated clinical research in neurocritical care. Such a system may help us overcome potential impediments to the future advancement of neurocritical care research. We propose the creation of the neurocritical care research network. The mission of the Network is to facilitate multicenter and multidisciplinary collaboration and patient enrollment in clinical trials of specific neurocritical care diseases.

Appendix

The First Neurocritical Care Research Conference Investigators are listed below:

Organizing Committee Chair: Suarez JI, MD, Baylor College of Medicine, Houston, TX; Calvillo E, RN, Baylor College of Medicine, Houston, TX; Geocadin R, MD, Johns Hopkins University, Baltimore, MD; Hall C, MD, UT Southwestern University; Le Roux PD, MD, University of Pennsylvania, Philadelphia, PA; Livesay S, MS, RN, ACNP, St Luke’s Episcopal Hospital, Houston, TX; Mayer SA, MD, Columbia University, New York, NY; Vespa P, MD, UCLA, Los Angeles, CA; Wijman C, MD, Stanford University, Palo Alto, CA; Zaidat OO, MD, MS, Medical College of Wisconsin, Milwaukee, WI.

Speakers Bleck TP, RUSH School of Medicine, Chicago, IL; Chang C, MD, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI; Cooper DJ, MD, Alfred Hospital and Monash University, Melbourne, Australia;

Guntupalli KK, MD, Baylor College of Medicine, Houston, TX; Daily J, PhD, Case Western Reserve University, Cleveland, OH; Diringer MA, MD, Washington University School of Medicine, St Louis, MO; Robertson CS, MD, Baylor College of Medicine, Houston, TX; Hanley DF, MD, Johns Hopkins University, Baltimore, MD;

Hemphill C III, MD, PhD, University of California in San Francisco, San Francisco, CA; Koroshetz W, MD, Deputy Director, NINDS, Bethesda. MD;

Mirski MA, MD, PhD, Johns Hopkins University, Baltimore, MD; Palesch Y, PhD, Medical University of South Carolina; Qureshi AI, MD, University of Minnesota, Minneapolis, MN; Silbergleit R, MD, University of Michigan, Ann Arbor, MI;

Smirnakis SM, MD, PhD, Baylor College of Medicine, Houston, TX; Szigeti K, MD, PhD, Baylor College of Medicine, Houston, TX.

Attendees Adeoye O, MD, University of Cincinnati College of Medicine, Cincinnati, OH; Aisiku IP, University of Texas in Houston, Houston, TX; Bader MK, RN, Mission Viejo Hospital, Mission Viejo, CA; Ansari S, MD, Baylor College of Medicine, Houston, TX; Arshad ST, MD, Baylor College of Medicine, Houston, TX; Badjatia N, MD, Columbia University, New York, NY; Barazangi N, MD, Ph.D., Califorrnia Pacific Medical Center, San Francisco, CA; Bershad EM, MD, Baylor College of Medicine, Houston, TX; Boyd C, RN, MBA, St Luke’s Episcopal Hospital, Houston, TX; Claassen J, MD, Columbia University, New York, NY; Coplin W, MD, Wayne State University, Detroit, MI; Corry JJ, Henry Ford Hospital, Detroit, MI; Cruz-Florez S, MD, St Louis University, St Louis, MO; Dhar R, MD, Washington University School of Medicine, St Louis, MO; Dillon C, MS, Medical University of South Carolina, Charleston, SC; Divani AA, Ph.D., University of Minnesota, Minneapolis, MN; Duckworth E, MD, Baylor College of Medicine, Houston, TX; Ezzedine M, MD, University of Minnesota, Minneapolis, MN; Feen E, MD, St Louis University, St Louis, MO; Freeman W, MD, Mayo Clinic Florida, Jacksonville, FL; Frontera J, MD, Mount Sinai School of Medicine, New York, NY; Goodman JC, MD, Baylor College of Medicine, Houston, TX; Graffagnino C, MD, Duke University, Durham, NC; Hoesch RE, MD, PhD, Johns Hopkins University, Baltimore, MD; Ko NU, MD, University of California in San Francisco, San Francisco, CA; Koening M, MD, Johns Hopkins University, Baltimore, MD; Kramer A, University of Calgary, Calgary, AL, Canada; Lazaridis C, MD, Medical University of South Carolina, Charleston, SC; Lee JC, MD, Baylor College of Medicine, Houston, TX; Ling G, MD, PhD, US Armed Forces, Bethesda, MD; Macdonald RL, MD, Ph.D., University of Toronto, Toronto, ON, Canada; Malkoff M, MD, University of New Mexico, Albuquerque, NM; Mandava P, MD, Baylor College of Medicine, Houston, TX; Manno E, MD, Mayo Clinic, Rochester, MN; Martin H Renee, Ph.D., Medical University of South Carolina, Charleston, SC; Mawad M, MD, Baylor College of Medicine, Houston, TX; Mizrahi E, MD, Baylor College of Medicine, Houston, TX; McArthur DL, Ph.D., UCLA, Los Angeles, CA; Nathan B, MD, University of Virginia, Charlottesville, VA; Newmark M, MD, Baylor College of Medicine, Houston, TX; Nguyen T, PharmD, St Luke’s Episcopal Hospital, Houston, TX; Nyquist P, MD, Ph.D., The Johns Hopkins Hospital, Baltimore, MD; Oliveira J, Hospital San Rafael, Universidade Federale da Bahia, Salvador, Brazil; Olson DW, RN, PhD, Duke University, Durham, NC; Ougorets I, MD, New York Weil Medical College of Cornell University, New York, NY; Puppo C, MD, Universidad de la República, Montevideo, Uruguay; Pyne-Geithman G, Ph.D., University of Cincinnati, Cincinnati, OH; Rao CPV, Baylor College of Medicine, Houston, TX; Revuelto J, MD, Hospital Virgen del Rocio, Seville, Spain Rhoney D, PharmD, Detroit Receiving Hospital, Detroit, MI; Riviello J, MD, Baylor College of Medicine, Houston, TX; Sawaya R, MD, Baylor College of Medicine, Houston, TX; Seder D,MD, Maine Medical Center, Portland, ME; Sheth K, MD, Brigham and Women’s Hospital, Boston, MA; Souter M, MD, University of Washington, Seattle, WA; Strutt AM, Ph.D., Baylor College of Medicine, Houston, TX; Suri MFK, MD, University of Minnesota, Minneapolis, MN; Temes R, MD, RUSH Medical Center, Chicago, IL; Torbey MT, MD, MPH, Medical College of Wisconsin, Milwaukee, WI; Treggiari M, University of Washington, Seattle, WA; Urfy MZ, MD, Baylor College of Medicine, Houston, TX Varelas P, MD, Ph.D., Henry Ford Hospital, Detroit, MI; Wright W, MD, Emory University, Atlanta, GA; York MK, Ph.D., Baylor College of Medicine, Houston, TX; Ziai W, MD, Johns Hopkins University, Baltimore, MD; Zwillman M, MD, The Methodist Hospital, Houston, TX.