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Post-PCI Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation

  • Interventional Cardiology (S Rao, Section Editor)
  • Published:
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Abstract

The number of patients who undergo percutaneous coronary intervention (PCI) and additionally require chronic anticoagulation for a variety of indications is not insignificant. The choice of antithrombotic therapy after PCI in patients with chronic indications for anticoagulation therapy remains a challenge for interventional cardiologists, as the risk of bleeding must be adequately weighed against the benefit of preventing future ischemic events. While these clinical scenarios are encountered in approximately 10 % of patients undergoing PCI, current practice guidelines do not sufficiently guide physicians as to how to best treat these PCI patients requiring chronic anticoagulation. Notwithstanding the clinical difficulties of treating such patients, there are several recent studies and analyses that have assessed optimal antithrombotic strategies in the PCI population, and there are several others that are currently underway. This review evaluates the currently available data and clinical scenarios commonly encountered by treating physicians.

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Conflict of Interest

Mahesh V. Madhavan declares that he has no conflict of interest.

Ajay J. Kirtane reports institutional research grants (to Columbia University) from Medtronic Cardiovascular, Boston Scientific, Abiomed, Abbott Vascular, Vascular Dynamics, and Eli Lilly.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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  1. Herbert and Sandi Feinberg Interventional Cardiology and Heart Valve Center at Columbia University Medical Center/New York-Presbyterian Hospital, 161 Fort Washington Avenue, 6th Floor, New York, NY, 10032, USA

    Mahesh V. Madhavan & Ajay J. Kirtane

  2. Cardiovascular Research Foundation, New York, NY, USA

    Mahesh V. Madhavan & Ajay J. Kirtane

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  1. Mahesh V. Madhavan
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Correspondence to Ajay J. Kirtane.

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Madhavan, M.V., Kirtane, A.J. Post-PCI Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation. Curr Cardiol Rep 17, 41 (2015). https://doi.org/10.1007/s11886-015-0598-4

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