Skip to main content

Advertisement

Log in

Bronchiolitis obliterans organizing pneumonia (BOOP) after renal transplantation

  • Nephrology – Case Report
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

A 42-year-old renal transplant recipient was admitted with fever, anorexia, malaise, nonproductive cough, and dyspnea of 1-week duration. Multiple cultures of blood, sputum, and urine were negative. The possibility of bronchiolitis obliterans with organizing pneumonia (BOOP) was considered when pulmonary infiltrate did not respond to conventional antibiotic therapy. High-resolution computed tomography of the chest revealed patchy air-space consolidation and ground-glass opacities, predominantly located in the periphery of the lungs. Cultures and stains of bronchoalveolar lavage specimen and bronchoscopic biopsy of lung tissue were negative for organisms such as Pneumocystis (carinii) jiroveci, bacteria, Mycobacterium tuberculosis, cytomegalovirus, fungi, and atypical germs, and showed evidence of BOOP. The patient recovered completely after treatment with steroids.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

References

  1. Jha V (2010) Post-transplant infections: an ounce of prevention. Indian J Nephrol 20:171–178

    Article  PubMed  CAS  Google Scholar 

  2. Kalra V, Agarwal SK, Khilnani GC, Kapil A, Dar L, Singh UB et al (2005) Spectrum of pulmonary infections in renal transplant recipients in the tropics: a single center study. Int Urol Nephrol 37:551–559

    Article  PubMed  Google Scholar 

  3. Dharnidharka VR, Stablein DM, Harmon WE (2004) Post-transplant infections now exceed acute rejection as cause for hospitalization: a report of the NAPRTCS. Am J Transplant 4:384–389

    Article  PubMed  Google Scholar 

  4. White KA, Ruth-Sahd LA (2007) Bronchiolitis obliterans organizing pneumonia. Crit Care Nurse 27:53–66; quiz 67

    Google Scholar 

  5. Verberckmoes R, Verbeken E, Verschakelen J, Vanrenterghem Y (1996) BOOP (bronchiolitis obliterans organizing pneumonia) after renal transplantation. Nephrol Dial Transplant 11:1862–1863

    Article  PubMed  CAS  Google Scholar 

  6. Cunha BA, Syed U, Mickail N (2011) Renal transplant with bronchiolitis obliterans organizing pneumonia (BOOP) attributable to tacrolimus and herpes simplex virus (HSV) pneumonia. Heart Lung Oct 11. [Epub ahead of print]

  7. Champion L, Stern M, Israël-Biet D, Mamzer-Bruneel MF, Peraldi MN, Kreis H et al (2006) Brief communication: sirolimus-associated pneumonitis: 24 cases in renal transplant recipients. Ann Intern Med 144:505–509

    Article  PubMed  Google Scholar 

  8. Carreño CA, Gadea M (2007) Case report of a kidney transplant recipient converted to everolimus due to malignancy: resolution of bronchiolitis obliterans organizing pneumonia without everolimus discontinuation. Transplant Proc 39:594–595

    Article  PubMed  Google Scholar 

  9. Bitzan M, Ouahed JD, Carpineta L, Bernard C, Bell LE (2010) Cryptogenic organizing pneumonia after rituximab therapy for presumed post-kidney transplant lymphoproliferative disease. Pediatr Nephrol 25:1163–1167 (Epub 2010 Feb 6)

    Google Scholar 

  10. Epler GR, Colby TV, McLoud TC, Carrington CB, Gaensler EA (1985) Bronchiolitis obliterans organizing pneumonia. N Engl J Med 312:152–158

    Article  PubMed  CAS  Google Scholar 

  11. Chapman JR, O’Connell PJ, Nankivell BJ (2005) Chronic renal allograft dysfunction. J Am Soc Nephrol 16(10):3015–3026 (Epub 2005 Aug 24)

    Google Scholar 

  12. Kadambi PV, Murphy B, Sheridan AM Differential diagnosis of renal allograft dysfunction. http://www.uptodate.com. [topic last updated: Feb 11, 2011, Literature review current through: Jan 2012]

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vivek B. Kute.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kute, V.B., Patel, M.P., Patil, S.B. et al. Bronchiolitis obliterans organizing pneumonia (BOOP) after renal transplantation. Int Urol Nephrol 45, 1517–1521 (2013). https://doi.org/10.1007/s11255-012-0182-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-012-0182-4

Keywords

Navigation