We studied in vitro modifying effect of high-density lipoproteins, low-density lipoproteins, very-low-density lipoproteins, and apolipoproteins A-I, C, and E on membrane structure of rat erythrocytes. Incubation of erythrocyte membranes with lipoproteins was accompanied by significant changes in the behavior of fluorescent probe pyrene in the hydrophobic membrane region. The regulatory effect of lipoproteins was probably realized via exchange of lipid components between these particles and erythrocyte membrane. Apolipoproteins probably had membranotropic activity. Apolipoproteins A-I, C, and E had various effects on biophysical properties of the lipid phase in erythrocyte membranes.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. A. Boldyrev, Introduction to Membranology [in Russian], Moscow (1990).
Yu. A. Vladimirov and G. E. Dobretsov, Fluorescent Probes in Study of Biological Membranes [in Russian], Moscow (1980).
R. Gennis, Biological Membranes: Molecular Structure and Function [in Russian], Moscow (1997).
G. E. Dobretsov, Fluorescent Probes in Study of Cells, Membranes, and Lipoproteins [in Russian], Moscow (1989).
N. A. Klimov and N. G. Nikul’cheva, Lipids, Lipoproteins, and Atherosclerosis [in Russian], St. Petersburg (1999).
L. E. Panin, Determinant Systems in Physics, Chemistry, and Biology [in Russian], Novosibirsk (2006).
L. E. Panin, N. V. Ryazantseva, V. V. Novitskii, and N. V. Tokareva, Byull. Eksp. Biol. Med., 140, No. 10, 402-406 (2005).
L. E. Panin, N. I. Shalbueva, and L. M. Polyakov, Biol. Membrany, 18, No. 5, 400-405 (2001).
L. M. Polyakov and L. E. Panin, Uspekhi Sovr. Biol., 120, No. 3, 265-272 (2000).
E. B. Yarovaya, D. G. Vazhkii, and V. A. Metel’skaya, Seriya: Kriticheskie Tekhnologii. Membrany, No. 3, 13-19 (2003).
M. Broncel, J. Chojnowska-Jezierska, M. Koter-Michalak, and I. Franiak, Pol. Arch. Med. Wewn., 113, 531-537 (2005).
F. T. Hatch and R. S. Lees, Adv. Lipid Res., 6, 2-68 (1968).
S. H. Quarfordt and H. L. Hilderman, J. Lipid Res., 11, No. 6, 528-535 (1970).
H. Sprong, P. Van der Sluijs, and G. van Meer, Nat. Rev. Mol. Cell. Biol., 2, No. 7, 504-513 (2001).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 9, pp. 273-276, September, 2009
Rights and permissions
About this article
Cite this article
Panin, L.E., Butusova, V.N., Ryazantseva, N.V. et al. Effect of Blood Lipoproteins and Apolipoproteins A-I, C, and E on the Microviscosity of Erythrocyte Membranes. Bull Exp Biol Med 148, 385–388 (2009). https://doi.org/10.1007/s10517-010-0719-4
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-010-0719-4