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Phosphate transport processes in eukaryotic cells

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Conclusion

Much more work has been done on Pi transport processes, even in the last five years, than we have been able to mention in the space available. We have restricted our discussion to studies on mechanisms of transport or transport regulation, identification of transport proteins and their essential amino acids, and isolation, purification, and reconstitution of Pi transport systems. Many valuable studies on the physiology of Pi transport and its regulation and Pi transport in nonepithelial cells have also been conducted. Transport of Pi into and out of organelles other than the mitochondrion is gaining well-deserved attention, as are transport processes in fungi and plants. It is hoped that in another five years many Pi transport processes will be understood in true molecular terms and that this will increase our knowledge of cellular bioenergetics and metabolism.

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References

  • Ambudkar, S.V., Maloney, P.C. 1984.J. Biol. Chem. 259:12576–12585

    PubMed  Google Scholar 

  • Amiel, C., Kuntziger, H., Richet, G. 1970.Pflueger's Arch. 317:93–109

    Google Scholar 

  • Amstutz, M., Mohrmann, M., Gmaj, P., Murer, H. 1985.Am. J. Physiol. 248:F705-F710

    Google Scholar 

  • Aquila, H., Eiermann, W., Klingenberg, M. 1982a.Eur. J. Biochem. 122:133–139

    PubMed  Google Scholar 

  • Aquila, H., Link, T.A., Klingenberg, M. 1985.EMBO J. 4:2369–2376

    PubMed  Google Scholar 

  • Aquila, H., Link, T.A., Klingenberg, M. 1987.FEBS Lett. 212:1–9

    PubMed  Google Scholar 

  • Aquila, H., Misra, D., Eulitz, M., Klingenberg, M. 1982b.Hoppe-Seyler's Z. Physiol. Chem. 363:345–349

    PubMed  Google Scholar 

  • Banerjee, R.K., Racker, E. 1979.Membr. Biochem. 2:203–225

    PubMed  Google Scholar 

  • Beliveau, R., Strevey, J. 1987.Kidney Int. 31:160

    Google Scholar 

  • Berghout, A., Raida, M., Romano, L., Passow, H. 1985.Biochim. Biophys. Acta 815:281–286

    PubMed  Google Scholar 

  • Berner, W., Kinne, R., Murer, H. 1976.Biochem. J. 160:467–474

    PubMed  Google Scholar 

  • Bisaccia, F., Palmieri, F. 1984.Biochim. Biophys. Acta 766:386–394

    PubMed  Google Scholar 

  • Bonjour, J.-P., Caverzasio, J. 1984.Rev. Physiol. Biochem. Pharmacol. 100:161–214

    PubMed  Google Scholar 

  • Bowen, J.W., Levinson, C. 1983.J. Cell. Physiol. 116:142–148

    PubMed  Google Scholar 

  • Brahm, J. 1977.J. Gen. Physiol. 70:283–306

    Google Scholar 

  • Brodelius, P., Vogel, H.J. 1985.J. Biol. Chem. 260:3556–3560

    PubMed  Google Scholar 

  • Brown, C.D.A., Bodmer, M., Biber, J., Murer, H. 1984.Biochim. Biophys. Acta 769:471–478

    Google Scholar 

  • Brunette, M.G., Allard, S. 1985.Pediatr. Res. 19:1179–1182

    PubMed  Google Scholar 

  • Brunette, M.G., Beliveau, R. 1984.Adv. Exp. Med. Biol. 178:29–32

    PubMed  Google Scholar 

  • Brunette, M.G., Beliveau, R., Chan, M. 1984.Can. J. Physiol. Pharmacol. 62:229–234

    PubMed  Google Scholar 

  • Bukusoglu, C., Wohlrab, H. 1987.Biophys. J. 51:183a

    Google Scholar 

  • Burckhardt, G., Stern, H., Murer, H. 1981.Pflueger's Arch. 390:191–197

    Google Scholar 

  • Chappell, J.B., Robinson, B.H. 1968.Biochem. Soc. Symp. Cambridge 27:123–133

    Google Scholar 

  • Cheng, L., Liang, C.T., Sacktor, B. 1983.Am. J. Physiol. 245:F175-F180

    PubMed  Google Scholar 

  • Cheng, L., Sacktor, B. 1981.J. Biol. Chem. 256:1556–1564

    PubMed  Google Scholar 

  • Coty, W.A., Pedersen, P.L. 1974.J. Biol. Chem. 249:2593–2598

    PubMed  Google Scholar 

  • Coty, W.A., Pedersen, P.L. 1975a.J. Biol. Chem. 250:3515–3521

    PubMed  Google Scholar 

  • Coty, W.A., Pedersen, P.L. 1975b.Mol. Cell. Biochem. 9:109–124

    PubMed  Google Scholar 

  • Craik, J.D., Gounden, K., Reithmeier, R.A.F.. 1986.Biochim. Biophys. Acta 856:602–609

    PubMed  Google Scholar 

  • Craik, J.D., Reithmeier, R.A.F. 1985.J. Biol. Chem. 260:2404–2408

    PubMed  Google Scholar 

  • Danisi, G., Murer, H., Straub, R.W. 1984.Adv. Exp. Med. Biol. 178:173–180

    PubMed  Google Scholar 

  • Danisi, G., van Os, C.H., Straub, R.W. 1984.Prog. Clin. Biol. Res. 168:229–234

    PubMed  Google Scholar 

  • Debiec, H., Lorenc, R. 1984.Prog. Clin. Biol. 168:349–353

    Google Scholar 

  • Dennis, V.W., Brazy, P.C. 1982.Kidney Int. 22:498–506

    PubMed  Google Scholar 

  • Desmoulins, F., Cozzone, P.J., Canioni, P. 1987.Eur. J. Biochem. 162:151–159

    PubMed  Google Scholar 

  • Erecińska, M., Stubbs, M., Miyata, Y., Ditre, C.M., Wilson, D.F. 1977.Biochim. Biophys. Acta 462:20–35

    PubMed  Google Scholar 

  • Ferreira, G.C., Pratt, R.D., Pedersen, P.L. 1989.Fed. Proc. (in press)

  • Fliege, R., Flügge, U.I., Werdan, K., Heldt, H.W. 1978.Biochim. Biophys. Acta 502:232–247

    PubMed  Google Scholar 

  • Flügge, U.I., Fischer, K., Gross, A., Sebald, W., Logttspeich, F., Eckerskorn, C. 1989.EMBO J. 8:39–46

    PubMed  Google Scholar 

  • Flügge, U.I., Gerber, J., Heldt, H.W. 1981.Biochim. Biophys. Acta 725:229–237

    Google Scholar 

  • Flügge, U.I., Heldt, H.W. 1979.In: Function and Molecular Aspects of Biomembrane Transport. E. Quagliaiello et al., editors. pp. 373–382, Elsevier-North Holland, Amsterdam

    Google Scholar 

  • Flügge, U.I., Heldt, H.W. 1984.Trends Biochem. Sci. 9:530–533

    Google Scholar 

  • Fonyo, A. 1976.Pharmacol. Ther. 7:627–645

    Google Scholar 

  • Fonyo, A., Bessman, S.P. 1968.Biochem. Med. 2:145–163

    Google Scholar 

  • Fonyo, A., Vignais, P.V. 1980.J. Bioenerg. Biomembr. 12:137–149

    PubMed  Google Scholar 

  • Freeman, D.M., Chan, L., Yahaya, H., Holloway, P., Ross, B. 1986.Kidney Int. 30:35–42

    PubMed  Google Scholar 

  • Freitag, H., Kadenbach, B. 1978.Eur. J. Biochem. 83:53–57

    PubMed  Google Scholar 

  • Garlick, P.B., Brown, T.B., Sullivan, R.H., Ugurbil, K. 1983.J. Mol. Cell. Cardiol. 15:855–858

    PubMed  Google Scholar 

  • Gibb, G.M., Reid, G.P., Lindsay, J.G. 1986.Biochem. J. 238:543–551

    PubMed  Google Scholar 

  • Gmaj, P., Murer, H. 1986.Physiol. Rev 66:36–70

    PubMed  Google Scholar 

  • Goodman, J., Rothstein, A. 1957.J. Gen. Physiol. 40:915–923

    PubMed  Google Scholar 

  • Griffiths, D.G., Partis, M.D., Sharp, R.N., Beechey, R.B. 1982.Eur. Bioenerg. Conf. Rep. 2:635–636

    Google Scholar 

  • Guerin, B., Guerin, M., Klingenberg, M. 1970.FEBS. Lett. 10:265–268

    PubMed  Google Scholar 

  • Gunn, R.B., Kopito, R. 1989.Biophys. J. 55:146a

    Google Scholar 

  • Hamilton, R.T., Nilsen-Hamilton, M. 1978.J. Biol. Chem. 253:8247–8256

    PubMed  Google Scholar 

  • Hammerman, M.R., Hansen, V.A., Morrissey, J.J. 1983.Biochim. Biophys. Acta 755:10–16

    PubMed  Google Scholar 

  • Harris, C.A., Baer, P.G., Chirito, E., Dirks, H.H. 1974.Am. J. Physiol. 227:972–976

    Google Scholar 

  • Heldt, H.W., Rapley, L. 1970.FEBS Lett. 10:143–148

    PubMed  Google Scholar 

  • Hoffman, N., Thees, M., Kinne, R. 1976.Pflueger's Arch. 362:147–156

    Google Scholar 

  • Houstek, J., Pedersen, P.L. 1985.J. Biol. Chem. 260:6288–6295

    PubMed  Google Scholar 

  • Hruska, K., Kurnik, B., Tsutsumi, M. 1984.Adv. Exp. Med. Biol. 178:3–19

    PubMed  Google Scholar 

  • Jeanjean, A., Bedu, S., Rocca-Serra, J., Foucault, C. 1984.Arch. Microbiol. 137:215–219

    PubMed  Google Scholar 

  • Jeanjean, R., Fournier, N. 1979.FEBS Lett. 105:163–166

    PubMed  Google Scholar 

  • Jeffries, F.M.H., LaNoue, K.F. Radda, G.K. 1986.Biochemistry 25:7667–7675

    PubMed  Google Scholar 

  • Jennings, M.L. 1976.J. Membrane Biol. 28:187–205

    Google Scholar 

  • Jennings, M.L. 1982.J. Biol. Chem. 257:7554–7559

    Google Scholar 

  • Jennings, M.L. 1985.Annu. Rev. Physiol. 47:519–533

    PubMed  Google Scholar 

  • Jirounek, P., Rouiller, M., Jones, G.J., Straub, R.W. 1982.J. Membrane Biol. 65:125–130

    Google Scholar 

  • Jirounek, P., Vitus, J., Jones, G.J., Pralong, W.F., Straub, R.W. 1984.J. Membrane Biol. 79:87–95

    Google Scholar 

  • Kaplan, R.S., Pedersen, P.L. 1985.J. Biol. Chem. 260:10293–10298

    PubMed  Google Scholar 

  • Kaplan, R.S., Pratt, R.D., Pedersen, P.L. 1986.J. Biol. Chem. 261:12767–12773

    PubMed  Google Scholar 

  • Kessler, R.J., Vaughn, D.A., Fanestil, D.D. 1982.J. Biol. Chem. 257:14311–14317

    PubMed  Google Scholar 

  • Klingenberg, M., Riccio, P., Aquila, H. 1978.Biochim. Biophys. Acta 503:193–210

    PubMed  Google Scholar 

  • Koble, H.V.J., Costello, D., Wong, A., Lu, R.C., Wohlrab, H. 1984.J. Biol. Chem. 259:9115–9120

    PubMed  Google Scholar 

  • Kolbe, H.V.J., Wohlrab, H. 1985.J. Biol. Chem. 260:15899–15906

    PubMed  Google Scholar 

  • Legrum, B., Fasold, H., Passow, H. 1980.Hoppe-Seyler's Z. Physiol. Chem. 361:1573–1590

    PubMed  Google Scholar 

  • Lehninger, A.L., Reynafarje, B. 1982.Curr. Topics Cell. Regul. 18:329–341

    Google Scholar 

  • Ligeti, E., Brandolin, G., Dupont, Y., Vignais, P.V. 1985.Biochemistry 24:4423–4428

    PubMed  Google Scholar 

  • Ligeti, E., Fonyo, A. 1984.Eur. J. Biochem. 139:279–285

    PubMed  Google Scholar 

  • Lin, J.-T., Schwarc, K., Stroh, A. 1984.Biochim. Biophys. Acta 774:254–260

    PubMed  Google Scholar 

  • Lin, W. 1979.Plant Physiol. 63:952–955

    Google Scholar 

  • Lin, W. 1981.Plant Physiol. 68:435–438

    Google Scholar 

  • Macara, I.G., Cantley, L.C. 1983.In: Cell Membranes, Methods and Reviews. E. Elson, W. Frazier, and L. Glaser, editors. pp. 41–87. Plenum, New York

    Google Scholar 

  • Maloney, P.C., Ambudkar, S.V., Thomas, J., Schiller, L. 1984.J. Bacteriol. 158:238–245

    PubMed  Google Scholar 

  • Medina, G., Illingworth, J. 1980.Biochem. J. 188:297–311

    PubMed  Google Scholar 

  • Mende, P., Kolbe, H.V.J., Kadenbach, B., Stipani, I., Palmieri, F. 1982.Eur. J. Biochem. 128:91–95

    PubMed  Google Scholar 

  • Mitchell, P., Moyle, J. 1969.Eur. J. Biochem. 9:149–155

    PubMed  Google Scholar 

  • Mizgala, C.L., Quamme, G.A. 1985.Physiol. Rev. 65:431–466

    PubMed  Google Scholar 

  • Murer, H., Burckhardt, G. 1983.Rev. Physiol. Biochem. Pharmacol. 65:1–51

    Google Scholar 

  • Nieuenhuis, B.J.W.M., Borst-Pauwels, G.W.F.H. 1984.Biochim. Biophys. Acta 770:40–46

    PubMed  Google Scholar 

  • Nioka, S., Chance, B., Hilberman, M., Subramanian, H.V., Leigh, J.S., Jr., Veech, R.L., Forster, R.E. 1987.J. Appl. Physiol. 62:2094–2102

    PubMed  Google Scholar 

  • Noronha-Blob, L., Filburn, C., Sacktor, B. 1984.Arch. Biochem. Biophys. 234:265–274

    PubMed  Google Scholar 

  • Nuutinen, M., Hassinen, I. 1981.Biochem. Biophys. Acta 637:481–489

    PubMed  Google Scholar 

  • Palmieri, F., Prezioso, G., Quagliariello, E., Klingenberg, M. 1971.Eur. J. Biochem. 22:66–74

    PubMed  Google Scholar 

  • Peerce, B. 1988.Prog. Clin. Biol. Res. 252:73–80

    PubMed  Google Scholar 

  • Pratt, R.D., Pedersen, P.L. 1989.Arch. Biochem. Biophys. 268:9–19

    PubMed  Google Scholar 

  • Rasmussen, U.B., Wohlrab, H. 1986.Biochim. Biophys. Acta 852:306–314

    PubMed  Google Scholar 

  • Riccio, P., Aquila, H., Klingenberg, M. 1975.FEBS Lett. 56:129–132

    Google Scholar 

  • Roomans, G.M., Blasco, F., Borst-Pauwels, G.W.F.H. 1977.Biochim. Biophys. Acta 467:65–71

    PubMed  Google Scholar 

  • Roomans, G.M., Borst-Pauwels, G.W.F.H. 1979.Biochem. J. 178:521–527

    PubMed  Google Scholar 

  • Rosenberg, H., Gerdes, R.G., Harold, F.M. 1979.Biochem. J. 178:133–137

    PubMed  Google Scholar 

  • Rosenberg, H., Russell, L.M., Jacomb, P.A., Chegwidden, K. 1982.J. Bacteriol. 149:123–130

    PubMed  Google Scholar 

  • Runswick, M.J., Powell, S.J., Nyren, P., Walker, J.E. 1987.EMBO J. 5:1367–1373

    Google Scholar 

  • Runyon, K.R., Gunn, R.B. 1984.Biophys. J. 45:18a

    Google Scholar 

  • Sacktor, B., Cheng, L. 1981.J. Biol. Chem. 256:8080–8084

    Google Scholar 

  • Saint-Macary, M., Foucher, B. 1985.Biochem. Biophys. Res. Commun. 133:498–504

    PubMed  Google Scholar 

  • Saint-Macary, M., Laine, M., Foucher, B. 1979.Biochem. Biophys. Res. Commun. 113:170–174

    Google Scholar 

  • Saraste, M., Walker, J.E. 1982.FEBS Lett. 144:250–254

    PubMed  Google Scholar 

  • Schäli, C., Fanestil, D.D. 1985.Biochim. Biophys. Acta 819:66–74

    PubMed  Google Scholar 

  • Schäli, C., Vaughn, D.A., Fanestil, D.D. 1986.Biochem. J. 235:189–197

    PubMed  Google Scholar 

  • Schwab, S.J., Klahr, S., Hammerman, M.R., 1984a.Am. J. Physiol. 246:F663-F669

    PubMed  Google Scholar 

  • Schwab, S.J., Klahr, S., Hammerman, M.R. 1984b.Am. J. Physiol. 247:F543-F547

    PubMed  Google Scholar 

  • Shirazi-Beechey, S.P., Gorvel, J.-P., Beechey, R.B. 1988.J. Bioenerg. Biomembr. 20:273–288

    PubMed  Google Scholar 

  • Sonna, L.A., Maloney, P.C. 1988.J. Membrane Biol. 101:267–274

    Google Scholar 

  • Strevey, J., Brunette, M.G., Beliveau, R. 1984.Biochem. J. 223:793–802

    PubMed  Google Scholar 

  • Stulc, J., Stulcova, B. 1984.Placenta 5:9–19

    PubMed  Google Scholar 

  • Szczepanska-Konkel, M., Yusufi, A.H.K., Van Scoy, M., Webster, S.K., Dousa, T.P. 1986.J. Biol. Chem. 261:6375–6383

    PubMed  Google Scholar 

  • Ullrich-Eberius, C.I., Novacky, A., Fischer, E., Luttge, U. 1981.Plant. Physiol. 67:797–801

    Google Scholar 

  • Ullrich-Eberius, C.I., Novacky, A., van Bel, A.J.E. 1984.Planta 161:46–52

    Google Scholar 

  • Ullrich-Eberius, C.I., Yingchol, Y. 1974.Oecologia 17:17–26

    Google Scholar 

  • Warren, S., Williams, M.R. 1971.J. Chem. Soc. B:618–621

    Google Scholar 

  • Wehrle, J.P., Cintron, N.M., Pedersen, P.L. 1978.J. Biol. Chem. 253:8598–8603

    PubMed  Google Scholar 

  • Wehrle, J.P., Pedersen, P.L. 1981.J. Bioenerg. Biomembr. 13:285–294

    PubMed  Google Scholar 

  • Wehrle, J.P., Pedersen, P.L. 1982.J. Biol. Chem. 257:9698–9703

    PubMed  Google Scholar 

  • Wehrle, J.P., Pedersen, P.L. 1983.Arch. Biochem. Biophys. 223:477–483

    PubMed  Google Scholar 

  • Weith, J.O., Bjerrum, P.J., Borders, C.L. 1982.J. Gen. Physiol. 79:283–312

    PubMed  Google Scholar 

  • Wohlrab, H. 1979.In: Function and Molecular Aspects of Biomembrane Transport. E. Quagliariello, et al., editors. p. 387. Elsevier/North Holland. Amsterdam

    Google Scholar 

  • Wohlrab, H. 1980.J. Biol. Chem. 255:8170–8173

    PubMed  Google Scholar 

  • Wohlrab, H. 1986.Biochim. Biophys. Acta 853:115–134

    PubMed  Google Scholar 

  • Wohlrab, H., Collins, A., Costello, D. 1984a.Biochemistry 23:1057–1064

    Google Scholar 

  • Wohlrab, H., Flowers, N. 1982.J. Biol. Chem. 257:28–31

    PubMed  Google Scholar 

  • Wohlrab, H., Kolbe, H.V.J., Rasmussen, U.B., Collins, C. 1984b.Prog. Clin. Biol. Res. 168:211–216

    PubMed  Google Scholar 

  • Ysern, X., Amzel, L.M., Pedersen, P.L. 1988.J. Bioenerg. Biomembr. 20:423–449

    PubMed  Google Scholar 

  • Zweier, J.L., Jacobus, W.E. 1987.J. Biol. Chem. 262:8015–8021

    PubMed  Google Scholar 

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Wehrle, J.P., Pedersen, P.L. Phosphate transport processes in eukaryotic cells. J. Membrain Biol. 111, 199–213 (1989). https://doi.org/10.1007/BF01871006

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