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Pathology of the Mycoses in Patients with the Acquired Immunodeficiency Syndrome (AIDS)

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Current Topics in Medical Mycology

Part of the book series: Current Topics in Medical Mycology ((CT MYCOLOGY,volume 1))

Abstract

The acquired immunodeficiency syndrome (AIDS) is an often fatal illness characterized by a profound derangement in cell-mediated immunity (CMI), leading to multiple opportunistic infections and unusual neoplasms (10, 18, 23, 28). Epidemiologic evidence indicates that this syndrome, which was first reported in the spring of 1981 (8, 9), is transmissible sexually and by parenteral exposure to blood or blood products. Recent virologic and serologic studies suggest a causal link between AIDS and infection with an as yet unclassified retrovirus (3, 12, 21) related to the human T-lymphotropic retroviruses (20). Impaired CMI in AIDS patients is thought to be caused by infection of and reduction in the number of T-helper lymphocytes by this virus, which was first isolated from a lymph node of a homosexual man with unexplained lymphadenopathy and was tentatively called lymphadenopathy-associated virus (3).

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Authors
  1. Francis W. Chandler
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Editors and Affiliations

  1. Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA

    Michael R. McGinnis

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© 1985 Springer-Verlag New York, Inc.

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Chandler, F.W. (1985). Pathology of the Mycoses in Patients with the Acquired Immunodeficiency Syndrome (AIDS). In: McGinnis, M.R. (eds) Current Topics in Medical Mycology. Current Topics in Medical Mycology, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9547-8_1

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  • DOI: https://doi.org/10.1007/978-1-4613-9547-8_1

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-9549-2

  • Online ISBN: 978-1-4613-9547-8

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